Bioenergetics Flashcards
Flow of energy in a biological system
Bioenergetics
Large to small molecules
Catabolism
Small to large molecules
Anabolism
Energy releasing
Exergonic
Require energy
Endergonic
Total of all catabolic and anabolic reactions
Metabolism
Breakdown of one molecule of ATP to yield energy
Hydrolysis
Catalyzes ATP
ATPase
Phosphagen and first phase of glycolysis occur in
Sarcoplasm
Oxidative occurs in
Mitochondria
Only these can be metabolized for energy without direct involvement of oxygen…
Carbs
Contribution of energy system based on…
Intensity and then duration
Provides ATP primarily for short term high intensity
Phosphagen system
Phosphagen system relies on…
Hydrolysis of ATP and breakdown of creatine phosphate.
Drives direction of reactions…
Law of mass Action
Breakdown of carbs to resynthesize ATP
Glycolysis
End rest of glycolysis
Pyruvate
Two things cA happen to pyruvate…
Converted to lactate. Shuttled to mitochondria
When converted to lactate, ATP resynthesis occurs…
At a faster rate, but duration is shorter. Fast glycolysis
When sent to mitochondria for krebs, ATP resynthesis rate is…
Slower but longer in duration. Slow glycolysis.
If energy is needed at a high rate, pyruvate is…
Converted to lactate
If energy demand is not high and cell has sufficient oxygen…
Pyruvate sent to mitochondria
Leading to krebs, this is transported to mitochondria
Pyruvate And 2 NADH
Pyruvate converted to
Acetyl coA
NADH enters…
The ETC
Process of adding Pi to another molecule..
Phosphorylation
Direct resynthesis of ATP from ADP during single reaction in metabolic pathways
Substrate level
Resynthesis of ATP in ETC is called..
Oxidative phosphorylation
Gross ATP resyntesized as a result of substrate level…
4
Blood glucose requires..
1 ATP
Muscle glucose..
Doesn’t require ATP
Rate limiting step of glycolysis..
PFK
Intensity at which blood lactate begins an abrupt increase above baseline concentrations
Lactate threshold
Second point of inflection at higher intensities..
OBLA
Primary source of ATP at rest and during low intensity activities
Oxidative system
One NADH can produce
3 ATP
One FADH2 can produce
2 ATP
Oxidative system results in how many ATP from one glucose
38
Free fatty Acids are broken down by
Beta oxidation
Major amino acids that are oxidized in skmm
BCAAs
Rate limiting step of oxidative system
Isocitrate dehydrogenase
Appropriate exercise intensities and rest intervals can permit selection of specific energy systems
Metabolic specificity of training
Typical exercise time for phosphagen
5 to 10 seconds
Time for fast glycolysis
15 to 30 seconds
Time for fast glycolysis and oxidative
1 to 3 minutes
Time for oxidative
> 3 minutes