Bioenergetics Flashcards

1
Q

when fuels are oxidized they produce

A

water and carbon dioxide

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2
Q

phase 1 of respiration is

A

oxidation of fuels

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3
Q

phase 2 of respiration is

A

ATP generation from oxidation phosphorylation

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4
Q

bioenergetics of the cell

A

the transformation and utilization of energy in the cell

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5
Q

what tissue requires the msot ATP per gram of tissue

A

kidneys

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6
Q

does skeletal muscle while running or the heart require for ATP/g of tissue

A

skeletal muscle while running

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7
Q

gibbs free energy

A

total energy in a system which is available to do work

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8
Q

delta G is

A

the change in free energy which occurs in a chemical process

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9
Q

formula for delta G

A

delta H-Ts

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10
Q

delta H

A

enthalpy change (chagne in heat)

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11
Q

delta S

A

entropy change (change in disorder)

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12
Q

when delta G is negative

A

we have lost energy, reaction is spontaneous and is exergonic

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13
Q

when delta G is positive

A

net gain of energy, reaction will not go spontaneously, reaction is endergonic and energy must be supplied to make the reaction go S-P

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14
Q

when delta G is zero

A

reaction is at equilibrum

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15
Q

delta G not

A

free energy change under standard conditions ( 25C and ph 7)

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16
Q

delta G not prime=

A

-rtln (Keq)

17
Q

what does delta Gnot prime provide

A

uniform convention for measuring free energy changes and a definition of where the equilibrium lies

18
Q

the delta G for the overal reaction is the

A

sum of the individual reactions

19
Q

what are the three methods for producing ATP

A

substrate level phosphorylation, direct attachment of phosphate or by a transfer of a high energy metabolite

20
Q

succinate thiokinase reaction is an example of

A

ATP by direct attachment of a phosphate

21
Q

examples of compounds with high energy phosphate bonds

A

1,3 BPG
PEP
creatine phosphate
acetyl CoA

22
Q

what is the high energy phosphate reservoir in the brain, muscle and psermatozoa ?

A

creatine phosphate

23
Q

where is the ETC located

A

inner mitochondrial membrane

24
Q

NAD is synthesized from

A

niacin

25
Q

FAD is made from

A

riboflavin (vitamin B2)

26
Q

the reduction of NAD results in

A

NADH

27
Q

most of our ATP is produced by

A

oxidative phosphorylation except in hypoxic circumstances

28
Q

in hypoxia you have a decrease or increase in pH

A

decrease (alcolosis)