Biochem Pages 82-91 Flashcards
Patient complaints that he can’t smell well and has a persistently rancid metallic taste in his mouth. On physical exam, there is evidence of hypogonadism, sparse pubic, facial, and axillary hair. What deficiency is suspected?
Zinc
2016; Pg 82
Acrodermatitis enteropathica is associated with which vitamin deficiency?
Zinc
2016; Pg 82
Malnourished child presents with a swollen abdomen, anemia, and impaired liver function. What disorder is present?
Kwashiorkor
(2016; Pg 82)
Edema is due to decreased oncotic pressure and liver malfunction to decreased apolipoprotein synthesis
Total caloric malnutrition resulting in tissue and muscle wasting and loss of subcutaneous fat.
Marasmus
2016; Pg 82
Antidote for methanol or ethylene glycol poisoning that Inhibits alcohol dehydrogenase
Fomepizole
2016; Pg 82
Drug given to discourage drinking that inhibits acetaldehyde dehydrogenase
Disulfiram
2016; Pg 83
Effect of chronic alcoholism on NADH/NAD+ ratio in liver
Increase
2016; Pg 83
Chronic intake of _____ is known to induce lactic acidosis, fasting hypoglycemia, and hepatosteatosis.
Ethanol
2016; Pg 83
Cellular site for fatty acid beta oxidation, acetyl-CoA production, TCA cycle, oxidative phosphorylation, and ketogenesis.
Mitochondria
2016; Pg 83
Cellular site for glycolysis, HMP shunt, and the synthesis of steroids, proteins, fatty acids, cholesterol, and nucleotides.
Cytoplasm
2016; Pg 83
Where do heme synthesis, the urea cycle, and gluconeogenesis occur?
Both the mitochondria and cytoplasm
(2016; Pg 83)
HUGs take two
Relocates a functional group within a molecule
Mutase
2016; Pg 84
Co-factor in the transfer of CO2 groups by carboxylases
Biotin
2016; Pg 84
Rate-determining enzyme of glycolysis
Phosphofructokinase-1 (PFK-1)
2016; Pg 84
Fructose-1,6-bisphosphatase is the rate-determining enzyme for which metabolic process?
Gluconeogenesis
2016; Pg 84