Biochem 10-31-2013 cell membrane structure Flashcards
(lipid bilayer/transport protiens/receptor proteins/celltocell protein interactions)
is relatively impermeable to a large number of different solutes, this allows the cell to maintain discrete composition in these compartments and to localize specific functions to specific compartments. Allows different metabolic processes to occur simultaneously.
lipid bilayer
(lipid bilayer/transport protiens/receptor proteins/celltocell protein interactions)
-the membrane regulates the rate of entry/exit of various, non-lipid soluble molecules. Endo- and exocytosis can be thought of in this category as well.
transport protiens
(lipid bilayer/transport protiens/receptor proteins/celltocell protein interactions)
-associated with the membrane, the cell has the capacity to receive, and act on, information about its external environment.
receptor proteins
(lipid bilayer/transport protiens/receptor proteins/celltocell protein interactions)
allowing the direct or indirect transfer of information between cells
cell to cell protein interaction
all cell generally forms a (square/triangle/spherical) shape in water, the only other material known to ehibit this behavior is (vinegar/oil). the (hydrogen/lipid) nature of the cell membrane was first instuited by this fact
spherical, oil, lipid
membrane lipids (are/arent) amphipathic
are
(fatty acids/phophoipids) are more cylindrical and natually form a two-layers bilayer
phospholipids
(fatty acids/phophoipids) cluster with thier polar head groups out and tails toward center forming micelles
fatty acids
lipid bilayers form sphere called ___
liposome
planar phospholipid bilayer is energetically (favored/unfavored)
unfavored
(hydrophilic/hydrophobic) molecules diffuse across the lipid bilayer
hydrophobic
permeability across the lipid bilayer is due to (size/polarity/hydrocarbons)-pick two
size polarity
name the two most abundant lipids in cell membranes
glyerophospholipids, sphingophospholipids
(glycolipids/sterols) are four ring hydrocarbon
sterols
(glycolipids/sterols) a complex molecule containing carbohydrates covalently bound to the lipid
glycolipids
(saturated/unsaturated) fatty acids have a kink and are not planar
unsaturated
(saturated/unsaturate) fatty acids are planar
saturated
why do unsaturated fatty acids have a kink what is it due to?
double bonds
the __ and ___ of the fatty acids have implications for the membrane and its fluidity
number of double bonds(degree of unsaturation) and number of carbons (length)
oleate and linoleate are (saturated/unsaturated)
unsaturated
palmitate and stearate are (saturated/unsaturated)
saturated
(sphingophospholipids/glycerophospholipds) glycerol , phosphate group, polar head group
glycerophospholipds
(PS/PE/PI/PC) which ones have a negative charge associated with the phophate group
PS,PI
- integral membrane proteins
- transmembrane
- lipid linked membrane protiens
- peripheral membrane proteins
: includes all proteins directly embedded with the lipid bilayer; contain significant number of hydrophobic amino acids that interact with the hydrocarbon chains of the lipid bilayer
- integral membrane proteins
are integral membrane proteins that completely span the bilayer and have hydrophilic domains interacting with both the ECF and ICF
- integral membrane proteins
- transmembrane
- lipid linked membrane protiens
- peripheral membrane proteins
- transmembrane
- integral membrane proteins
- transmembrane
- lipid linked membrane protiens
- peripheral membrane proteins
proteins may/may not be considered integral membrane proteins (depending on the source); however the protein itself is not embedded within the lipid bilayer, but it is covalently attached to hydrophobic fatty acids or prenyl side chains that are incorporated into the lipid bilayer
lipid linked membrane
- integral membrane proteins
- transmembrane
- lipid linked membrane protiens
- peripheral membrane proteins
are only associated with other membrane proteins by non-covalent interactions (H-bonds, ionic bonds, van der Waal attractions)
peripheral membrane proteins