beta lactams Flashcards
beta lactam classes
- Penicillins
- Cephalosporins
- Carbapenems
- Monobactam
N.penicillins are effective against:
G+ve ex: S. pyogenes
viridans faecalis
+ N.G
N.penicillins are ineffective against:
MRSA
G-VE
N. penicillins treat
Necrotizing faecalis
Syphilis
RF
Endocarditis
Anti-staph penicillins examples
nafcillin (IV)
Dicloxacillin (ORAL)
Anti-staph penicillins effective
MSSA , viridans , faecialis , pyogenes
Anti-staph penicillins ineffective
MRSA , B. fragilis , aerobic g-ve
Anti-staph penicillins treat
cellulitis , skin infections (SA)
Anti-Pseudomonas Penicillins examples
Piperacillin +/ tazocin ( with tazobactam)
Anti-Pseudomonas Penicillins effective
Alone: PA
Tazocin: anaerobes (BF) , Strep , MSSA
Anti-Pseudomonas Penicillins ineffective
MRSA , ESBL
Anti-Pseudomonas Penicillins treat
hospital & polymicrobial infections
(ps CAN’T TREAT MENINGITIS)
Anti-Pseudomonas ADVERSE EFFECTS
interstitial nephritis + nephrotoxicity (if combined with vancomycin)
Aminopenicillins examples
ampicillin , amoxicillin (helps absorption)
Aminopenicillins effective
enterococci , enterobacterals , strep (ex agalactiae) , listeria
Aminopenicillins ineffective
PA , MRSA
Aminopenicillins treat
Neonatal Meningitis , H.pylori , endocarditis , community inf , prophylaxis in preg.
cefazolin
1st generation