Benzodiazepines

Question 1

Moa

Answer 1

-bind with receptors in brain
-well absorbed with oral
-admin oral or parentally

Question 2

Indications

Answer 2

-sedation
-sleep induction
-skeletal muscle relaxation
-anxiety relief**
-anxiety r/t depression
-acute seizure
-alcohol withdrawal
-agitation
-balanced anesthesia**
-mod or conscious sedation

Question 3

Contraindications

Answer 3

-used with opioid analgesics, analgesic dose decrease then gradual increase
-older adult: resp depress, over sedate, dizzy, confuse, hypotension, impaired mobility
-hepatic/renal impairment: increased risk of AE—resp depress

Question 4

Nursing implications

Answer 4

-physical dependence with longer use/increase dose
-monitor for sx of withdrawal or recurrent of og sx
-never stop abruptly
-therapeutic and AE occur after 2-3 days

Question 5

Toxicity

Answer 5

-excessive sedation
-resp depress
-coma
-death

Question 6

Antidote

Answer 6

-flumazenil
-ramozicon

Question 7

Long acting

Answer 7

-clonazepam (klonopin)
-diazepam (Valium)
-flurazepam (dalmane)

Question 8

Intermediate

Answer 8

-alprazolam (Xanax)
-lorazepam (Ativan)
-temazepam (restoril)

Question 9

Short acting

Answer 9

-medazolam (versea)
-triazolam (halcion)
-eszopiclone (lunesta)
-zolpidem (ambien)