Benign Neoplasms

Question 1

Definition: pathologic new growth of tissue not controlled by normal regulatory functions and no regression after removal of stimulus?

Answer 1

neoplasm

Question 2

Give 2 examples of epithelial neoplasms:

Answer 2

1) HPV Human papilloma virus

2) Keratoacanthoma

Question 3

What does exophytic mean?

Answer 3

tending to grow outward beyond the surface epithelium from which it originates—used of tumors

Question 4

What does pedunculated mean?

Answer 4

pertaining to a structure with a stalk

Question 5

Your patient has a exophytic, often pedunculated, pink to white tumor on the soft palate. What is it?

Answer 5

Papilloma (subcategory of HPV)

Question 6

Your patient has some common warts on their hands. What are they?

Answer 6

verruca vulgaris (HPV2)

Question 7

Your patient has multiple, slightly exophytic warts around their genital area. What are they?

Answer 7

condyloma acuminatum (HPV 6/11)

Question 8

What treatment option is there for individuals that have a papilloma, verruca vulgaris, or condyloma acuminatum?

Answer 8

they are all benign and can be removed

Question 9

You discover an older patient has similar signs as skin cancer on the head and neck that they report has come on rather rapidly. It looks umbilicate with rolled borders. What is it and what is the Tx?

Answer 9

Keratoacanthoma

Tx - nothing. Will undergo involution

Question 10

This type of benign neoplasm must look identical clinically and present as asymptomatic, slowly growing submucosal masses?

Answer 10

mesenchymal

Question 11

Define verruciform?

Answer 11

surface irregular

Question 12

Your patient has a yellowish tumor on a fatty portion of his skin. What could it be?

Answer 12

Lipoma

Question 13

Your patient has a tumor on his hard palate or gingiva that is pink to white with surface irregularities. What is it?

Answer 13

verruciform xanthoma

Question 14

Your patient has two smooth muscle tumors in the uterus. One is normal color, but the other is reddish to purple. What are they?

Answer 14

Leiomyoma (fibroid)

Question 15

Your patient has a tongue tumor and said her doctor also found one on her heart. What could it be?

Answer 15

Rabdomyoma

Question 16

Your patient has a tongue tumor that is firm and fixed on palpation. Cell analysis reveals pseudoepitheliomatous hyperplasia (PEH). What could it be?

Answer 16

granular cell tumor

Question 17

Your patient has just had a female newborn and she points out a congenital tumor along the maxillary anterior alveolar ridge. She tells you the doctor told her it has no PEH. What could it be?

Answer 17

congenital epulis

Question 18

Your patient experienced trauma in his lower lip at the mental foramen. You also look in his mouth to find tumors on the lateral and anterior borders of the tongue. Upon palpation, he complains of pain. What is it?

Answer 18

Traumatic Neuroma

Question 19

Your patient has an asymptomatic light brown skin pigmentation on his skin. What could it be?

Answer 19

Neurofibroma (on skin but originates from nerve cells)(cafe au lait spots)

Question 20

Your patient has pigmentary defects in her iris. What are they?

Answer 20

Neurofibromas (Lisch spots)

Question 21

Your patient has a painless, freely movable encapsulated neoplasm within the sheath of a peripheral nerve. What is it?

Answer 21

Neurilemmoma

Question 22

Your patient tells you about her 1 year-old with maxillary anterior jaw tumor that is pigmented and appears radiolucent. The lab says the tumor cells are producing Vanilymadelic Acid (VMA) in serum and urine. What is it?

Answer 22

Melanotic neuroectodermal tumor of infancy

Question 23

Your patient has a mutation of RET gene (a photo-oncogene) on chromosome 10. He says 50% get it from autosomal dominant while 50% from somatic mutation. What is it?

Answer 23

Multiple Endocrine Neoplasia Type 3 (MEN3)

Question 24

You are walking through the mall and you see someone with tumors all over his face. What is it?

Answer 24

Neurofibromatosis