Benign Neoplasms Flashcards
Definition: pathologic new growth of tissue not controlled by normal regulatory functions and no regression after removal of stimulus?
neoplasm
Give 2 examples of epithelial neoplasms:
1) HPV Human papilloma virus
2) Keratoacanthoma
What does exophytic mean?
tending to grow outward beyond the surface epithelium from which it originates—used of tumors
What does pedunculated mean?
pertaining to a structure with a stalk
Your patient has a exophytic, often pedunculated, pink to white tumor on the soft palate. What is it?
Papilloma (subcategory of HPV)
Your patient has some common warts on their hands. What are they?
verruca vulgaris (HPV2)
Your patient has multiple, slightly exophytic warts around their genital area. What are they?
condyloma acuminatum (HPV 6/11)
What treatment option is there for individuals that have a papilloma, verruca vulgaris, or condyloma acuminatum?
they are all benign and can be removed
You discover an older patient has similar signs as skin cancer on the head and neck that they report has come on rather rapidly. It looks umbilicate with rolled borders. What is it and what is the Tx?
Keratoacanthoma
Tx - nothing. Will undergo involution
This type of benign neoplasm must look identical clinically and present as asymptomatic, slowly growing submucosal masses?
mesenchymal
Define verruciform?
surface irregular
Your patient has a yellowish tumor on a fatty portion of his skin. What could it be?
Lipoma
Your patient has a tumor on his hard palate or gingiva that is pink to white with surface irregularities. What is it?
verruciform xanthoma
Your patient has two smooth muscle tumors in the uterus. One is normal color, but the other is reddish to purple. What are they?
Leiomyoma (fibroid)
Your patient has a tongue tumor and said her doctor also found one on her heart. What could it be?
Rabdomyoma
Your patient has a tongue tumor that is firm and fixed on palpation. Cell analysis reveals pseudoepitheliomatous hyperplasia (PEH). What could it be?
granular cell tumor
Your patient has just had a female newborn and she points out a congenital tumor along the maxillary anterior alveolar ridge. She tells you the doctor told her it has no PEH. What could it be?
congenital epulis
Your patient experienced trauma in his lower lip at the mental foramen. You also look in his mouth to find tumors on the lateral and anterior borders of the tongue. Upon palpation, he complains of pain. What is it?
Traumatic Neuroma
Your patient has an asymptomatic light brown skin pigmentation on his skin. What could it be?
Neurofibroma (on skin but originates from nerve cells)(cafe au lait spots)
Your patient has pigmentary defects in her iris. What are they?
Neurofibromas (Lisch spots)
Your patient has a painless, freely movable encapsulated neoplasm within the sheath of a peripheral nerve. What is it?
Neurilemmoma
Your patient tells you about her 1 year-old with maxillary anterior jaw tumor that is pigmented and appears radiolucent. The lab says the tumor cells are producing Vanilymadelic Acid (VMA) in serum and urine. What is it?
Melanotic neuroectodermal tumor of infancy
Your patient has a mutation of RET gene (a photo-oncogene) on chromosome 10. He says 50% get it from autosomal dominant while 50% from somatic mutation. What is it?
Multiple Endocrine Neoplasia Type 3 (MEN3)
You are walking through the mall and you see someone with tumors all over his face. What is it?
Neurofibromatosis
