Behavioral science Flashcards
Compares a group of people with disease to a group without disease - looks for prior exposure or risk factor
Case-control study (observational and retrospective)
Compares a group with a given exposure or risk factor to a group without such exposure - Looks to see if exposure increases the likelihood of the disease
Cohort study
Whats the difference between a retrospective and a prospective cohort study?
Prospective: asks “who will develop the disease”
Retrospective: asks “Who developed the disease”
How is prevalence determined from incidence rate and average disease duration?
Prevalence = incidence rate x average disease duration
Odds ratio
Odds that the group with the disease was exposed to a risk factor divided by the odds that the group without the disease was exposed
(a/c)/(b/d) or (ad)/(bc)
Relative risk (RR)
(a/(a+b))/(c/(c+d))
Relative risk reduction
The proportion of risk reduction attributable to the intervention as compared to a control
1-RR
Attributable risk
The proportion of disease occurrences that are attributable to the exposure
AR = (a/(a+b)) - (c/(c+d))
Absolute risk reduction
The difference in risk attributable to the intervention as compared to a control
If 8% of people who receive a placebo vaccine develop the flu vs 2% of people who receive a flu vaccine, then ARR = 8%-2%=6%
Number needed to treat
1/ARR
Number needed to harm
1/AR
Positive skew
Mean > Median > Mode
Tail on the right of the bell curve
Negative skew
Mean
If the 95% confidence interval for odds ratio or relative risk includes 1…
Null hypothesis is not rejected
If the 95% CI for a mean difference between 2 variables includes 0…
Then there is no significant difference