Bat Zoonosis (14) Flashcards
What is not a feature of bats?
a. They have a long life span
b. They have a high rate of tumour formation
c. They show variable thermoregulation
d. They are a reservoir for many viruses
b. They have a high rate of tumour formation
What is a feature of the Hendra and Nipah viruses?
a. They have a +ssRNA genome
b. They are in the coronaviridae family
c. They are henipavrisues in the paramyxoviridae family
d. They share identical morphology to measles and mumps viruses
c. They are henipavrisues in the paramyxoviridae family
What is not part of the Henipavirus viral protein?
a. The fusion and attachment proteins on the envelope
b. A nucleocapsid with L, N and P proteins
c. A segmented dsRNA genome
d. An 18.2kb genome
c. A segmented dsRNA genome
What was a feature of the 2011 Hendra Virus outbreak?
a. Over 200 pet dogs were infected
b. The outbreak location remained localised to Hendra
c. There was a 50% increase in spill over events
d. There was more Hendra virus shed in bat urine
d. There was more Hendra virus shed in bat urine
The host range of Nipah virus:
a. Can include bats, cats, dogs and pigs
b. Involves only humans and bats
c. Cannot be shown in cultured cells in vitro
d. Excludes all terrestrial species
a. Can include bats, cats, dogs and pigs
What is Ephrin B2?
a. A ligand receptor for Hendra and Nipah virus
b. A fusion receptor found on Coronaviridae
c. A unique receptor of the pig upper respiratory tract that interacts with paramyxoviridae
d. The protein subunit of the spikes found on coronaviruses
a. A ligand receptor for Hendra and Nipah virus
What is a feature of SARs-CoV?
a. It causes respiratory, enteric, orphan infection
b. It has an envelope spike which acts as an attachment and fusion protein
c. It has a –ssRNA genome
d. It is part of the paramyxoviridae family
b. It has an envelope spike which acts as an attachment and fusion protein
What were the consequences of the SARs outbreak?
a. Over 8000 deaths
b. Nearly 200 infections
c. 774 deaths
d. Nearly 100,000 infections
c. 774 deaths
What is a feature of MERS?
a. It uses the same receptor as SARS
b. It is 90% fatal
c. There have been 1368 confirmed cases
d. Camels are the source of infection
c. There have been 1368 confirmed cases
Why are bats often reservoirs for viruses?
a. They are less prone to immunopathology and inflammation
b. They have all the receptors that interact with human respiratory viruses
c. They have a short life span and viruses replicate quickly in bat cells
d. They often share habitats with humans who spread viruses to bats
a. They are less prone to immunopathology and inflammation
• Zoonosis is an infectious disease that can be transmitted from animals to humans.
T
• The henipavirus is smaller than other paramyxoviridae genomes due to having smaller coding regions.
F
• Nipah virus can only spread from bats to pigs to horses.
F (humans)
• Bangladesh Nipah virus can spread from bat to human and human to human only.
T
• Melaka virus has a unimolecular –ssRNA genome.
F (dsRNA segmented)
