Bacteriology - Mycology Intro Flashcards

1
Q

Importance of fungi being eukaryotic

A

Key for drug use, eukaryotic cells of fungi are similar to host cells - drugs can attack both = toxic

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2
Q

Ergosterol

A

Replaces cholesterol in fungi cells, what “azol” drug target

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3
Q

Yeast formation

A

Unicellular fungus, spreads by budding

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4
Q

Hyphae

A

Filamentous form of fungus

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5
Q

Pseudohyphae

A

Chains of yeast could appear like hyphae

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6
Q

Mold formation

A

Fungus that grows as a mass of hyphae (mycelium)

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7
Q

Dermatophyte form

A

Fungus that causes ringworm (superficial infections of skin, hair, nails)

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8
Q

Endospores

A

Spores contained in a sac

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9
Q

Dimorphism fungus

A

Fungus that exists as yeast forms in animal tissue & as hyphae in environment

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10
Q

Broad vs narrow based budding yeast

A

Broad - two spheres in one spore
Narrow - bowling pin shape

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11
Q

Fruiting body

A

Produces many conidia, tiny & light for easy dispersion (like a dandylion)

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12
Q

Arthroconidia

A

Spores released during hyphal fragmentation, occurs in patients

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13
Q

Macroconidia

A

Growth of spores that occur in vitro

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14
Q

Factors that effect development of fungal disease (5)

A

Virulence factors, tissues affected, host immunity, geographic location, environment

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15
Q

Best diagnostic test for superficial fungi

A

Wet mount cytology
- 10% K hydroxide
- new meth blue

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16
Q

Temps for sending out samples

A

Dermatophytes - room temp
Fungal disease - room temp
Bacterial contamination or differential diagnosis - on ice to stall bacterial growth

17
Q

In house Dermatophyte media

A

DTM - Dermatophyte test media
RSM - rapid sporulated media

18
Q

DTM

A

pH indicator, turns red as Dermatophyte grows and eats protein (increases pH) false positives if you wait too long