Bacterial virulence factors Flashcards
1
Q
What are the 3 bacterial virulence factors?
A
- Protein A
- IgA protease
- M protein
2
Q
What are the two roles of Protein A?
A
- Binds Fc regions of IgG
2. Prevents opsonization and phagocytosis
3
Q
What is the name of the bug that has Protein A?
A
S. aureus
4
Q
What is the role of IgA protease?
A
- Cleaves IgA
2. Helps colonizes respiratory mucosa
5
Q
What bugs use IgA protease?
A
SHiN
S. pneumoniae
H. influenza type B
Neisseria
6
Q
What is the role of M protein?
A
Helps prevent phagocytosis
7
Q
What bacteria expresses M protein?
A
Group A strep
