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Respiratory Exam 2 > Bacterial Drug Guide Broken Down > Flashcards

Bacterial Drug Guide Broken Down Flashcards

1
Q

MOA of sulfonamides

A
  • folate synthesis inhibitors
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2
Q

sulfonamide drug to know

which are anti-pseudomonals

A
  • sulfamethoxazole
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3
Q

what drug do we combine sulfamethoxazole with

A
  • trimethoprim
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4
Q

MOA of flouroquinolones

A
  • DNA damaging

- inhibit DNA gyrase

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5
Q

fluoroquinolone drugs to know

which are anti-pseudomonals

A
  • ciprofloxacin (anti-pseudomonals)
  • levofloxacin (anti-pseudomonals)
  • moxifloxacin
  • gemifloxacin
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6
Q

what are the two classes of cell wall synthesis inhibitors

A
  • beta lactams

- glycopeptides

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7
Q

what are the drug classes in the beta lactam class?

A
  • penicillins
  • monobactams
  • carbapenems
  • cephalosporins

MPCC Beta lactam

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8
Q

broad spectrum penicillins to know

which are anti-pseudomonals

A
  • ampicillin
  • amoxicillin
  • piperacillin (anti-pseudomonals)
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9
Q

monobactam drugs to know

which are anti-pseudomonals

A
  • aztreonam (anti-pseudomonals)
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10
Q

carbapenem drugs to know

which are anti-pseudomonals

A
  • imipenum (anti-pseudomonals)

- meropenum (anti-pseudomonals)

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11
Q

cephalosporin drugs to know

which are anti-pseudomonals

A
  • cefuroxime
  • ceftriaxone
  • cefotaxime
  • cefpodoxime
  • ceftazidime (anti-pseudomonals)
  • cefepime (anti-pseudomonals)
  • ceftaroline
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12
Q

what drugs to combine with lactamase inhibitors?

A
  • monobactams

- carbapenems

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13
Q

lactamase inhibitors to know

which are anti-pseudomonals

A
  • clavulanic acid

- tazobactam

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14
Q

glycopeptides to know

which are anti-pseudomonals

A
  • vancomycin
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15
Q

what drug classes are protein synthesis inhibitors?

A
  • 30S

- 50S

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16
Q

what drug classes are 30S protein synthesis inhibitors?

A
  • aminoglycosides
  • tetracyclines

AT 30

17
Q

what drug classes are 50S protein synthesis inhibitors?

A
  • macrolides
  • oxazolidenones
  • streptogramins
  • lincosamides

50 is not SMOL

18
Q

aminoglycoside drugs to know

which are anti-pseudomonals

A
  • gentamycin (anti-pseudomonals)
  • tobramycin (anti-pseudomonals)
  • amikacin (anti-pseudomonals)
19
Q

tetracycline drugs to know

which are anti-pseudomonals

A
  • doxycycline
20
Q

macrolide drugs to know

which are anti-pseudomonals

A
  • erythromycin
  • clarithromycin
  • azithromycin

MACRO ACE

21
Q

macrolides are pretty much effective against all gram positive except for which organism?

A
  • H. flu
22
Q

oxazolidenone drugs to know

which are anti-pseudomonals

A
  • linezolid
23
Q

lincosamide drugs to know

which are anti-pseudomonals

A
  • clindamycin
24
Q

cell membrane disruptor classes of drugs

A
  • polymyxin B

- daptomycin

25
Q

polymyxin B drugs to know

which are anti-pseudomonals

A
  • polymyxin E (colistin) (anti-pseudomonals)
26
Q

all folate synthesis inhibitors work against which organism class (gram+ or gram-)

A
  • both
27
Q

all fluoroquinolones work against which organism class (gram+ or gram-)

A
  • both
28
Q

all broad spectrum penicillins work against which organism class (gram+ or gram-)

A
  • both
29
Q

all monobactams work against which organism class (gram+ or gram-)

A
  • gram negative
30
Q

all carbapenems work against which organism class (gram+ or gram-)

A
  • both
31
Q

most cephalosporins work against which organism class (gram+ or gram-)

except which one (and what does it work against)

A
  • both

- ceftazidime (gram negatives)

32
Q

all glycopeptides work against which organism class (gram+ or gram-)

A
  • gram negatives
33
Q

all aminoglycosides work against which organism class (gram+ or gram-)

A
  • both
34
Q

all tetracyclines work against which organism class (gram+ or gram-)

A
  • both
35
Q

all macrolides work against which organism class (gram+ or gram-)

except which organism in particular

A
  • gram positive

- gram negative H. flu

36
Q

all oxazolidenones work against which organism class (gram+ or gram-)

A
  • gram positives
37
Q

all lincosamides work against which organism class (gram+ or gram-)

A
  • both
38
Q

all polyxmin B’s work against which organism class (gram+ or gram-)

A
  • gram negative

Respiratory Exam 2 (18 decks)

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