Bacteria to know for Exam 2 Flashcards
1
Q
Chlamydia
A
- Gram negative
- Obligate intracellular
- no muramic acid or peptidoglycan
- no carbohydrate metabolism
- cause
- chlamydia
2
Q
Yersinia
A
- Gram negative
- Virulence factors
- Endotoxin
- live in phagocyte
- mode of transmission
- droplet
- Flea is vector
- Causes
- Yersiia pestis causes plague (can be bubonic, pneumonic, or septicemic)
3
Q
Mycoplasma
A
- Sterol instead of peptidoglycan
- adhere to respiratory tract
- Transmission
- droplet
- Cause
- primary atypical pneumonia
- UTI- ureoplasma
4
Q
Borrelia
A
- Virulence factors
- Axial filament
- for motility
- Axial filament
- Vector
- Ticks
- Reservoir
- Field mice
- Disease
- Lyme disease
- 3 stages
- bullseye rash, arthritis, and neurological symptoms
- 3 stages
- Lyme disease
5
Q
Myobacterium
A
- Causes:
- Tuberculosis
- M. Boris, M. tuberculosis
- Leprosy
- M. leprae
- M. avium complex
- pulmonary infection GI infection
- Tuberculosis
- Virulence factors:
- mycolic acid
- escape phagocytosis
- Multi-drug resistance
- Transmission
- Droplet
- Prolonged exposure (leprosy)
6
Q
Clostridium
A
- Gram positive
- Virulence factors
- Spore forming
- neurotoxin (botulism and tetani)
- Causes
- C. tetani causes tetanus (rigid paralysis), c. botulinum causes botulism (flaccid paralysis)
- C. perfringens causes gas gangrene
- C. difficile causes diarrhea
7
Q
Helicobacter
A
- Gram negative
- Virulence factors
- fimbriae
- urease
- converts urea to ammonia to CO2
- flagella
- Transmission
- person to person
- Causes
- Peptic ulcers
8
Q
Lactobacillus
A
- gram postive
- normal mirobiota of:
- mouth, intestine, and vagina
- cause:
- dental carries
- Produce H2O2 in vagina
- found in yogurt
9
Q
Listeria
A
- Gram positive
- Virulence factors:
- Reproduce in phagocytes
- flagella
- grows in refridgerator
- use host actin to propel cell to cell
- transmission
- Food-borne
- diseases Listeriosis
10
Q
Leptospira
A
- Gram negative
- Spirochete
- Reservoirs
- Dogs
- Rats
- contaminated drinking water
- Causes
- biphasic: aches, fever, meningitis, kidney/liver failure, and respiratory distress
11
Q
Treponema
A
- Gram negative
- Spirochete
- so have axial filament for motility
- Transmission
- Sexual
- In utero
- Disease
- Syphilis
- 3 stages
- ulcers
- rash on palms and soles
- gummas
- 3 stages
- Syphilis
12
Q
Bacillus
A
- Gram positive
- Virulence factors
- Exotoxin
- Capsule
- Causes
- Food poisoning- B. cereus
- Anthrax poisoning- B. Authracis
- anthrax is contracted via GI> Cutaneous> pulmonary)
13
Q
Neisseria
A
- Gram negative
- virulence factors
- Catalase
- capsule
- fimbriae
- opa protein (prevents CD34 prolieration)
- S pili (decoys)
- Transmission
- droplet
- Causes
- gonorrhea
- meningitis
14
Q
Klebisella
A
- Gram negative
- Virulence factors
- Flagella
- Capsules
- drug resistance
- Nitrogen fixation
- Causes
- pneumoniae- K. pneumoniae
15
Q
Campylobacter
A
- Gram negative
- Cytotoxin
- Revervoirs
- Water, food animals
- Causes
- Gastroenteritis- C. jejuni
- Guillain barre syndrome
16
Q
Corynebacterium
A
- Gram positive
- Virulence factors
- AB toxin (inhibits host protein synthesis)
- Transmission
- Airborne
- Disease
- Diptheria- C. diptheiae
17
Q
Pseudomonas
A
- Gram negative
- Virulence factors
- Drug resistant
- Efflux pumps
- Flagella
- opportunistic/nosocomial
- Drug resistant
- Causes
- swimmers ear
- post burn infections
- dermatitis
- blue/green pus
18
Q
Rickettsia
A
- Gram negative
- Virulence factors
- Escape phagosome
- Obligate intracellular pathogen
- Vector
- blood sucking anthropods (ticks)
- Causes
- Rocky mountain spotted fever
- rash on palm and sole
- typhus fever
- muscle aches
- Rocky mountain spotted fever
19
Q
Bordetella
A
- Gram negative
- virulence factors
- Capsule
- pertussis toxin (inhibits protein syntheis)
- tracheal cytotoxin (destroy epithelia)
- Transmission
- droplet
- Causes
- Pertussis/whooping cough (catarrhal, paroxysmal, convalescence stages)
20
Q
Legionella
A
- Gram negative
- Virulence factors
- Hsp 60
- invasion in alveolar macrophage
- transmission
- airborn
- water
- Causes
- legionnaires disease
- pontiac fever
21
Q
Salmonella
A
- Gram negative
- Virulence factors
- Endotoxin
- cytotoxin
- Transmission
- Food
- Causes
- Salmonellosis
- Typhoid fever
22
Q
Escherichia
A
- Gram Negative
- Virulence factors
- Endotoxin
- O antigen (LPS)
- K antigen (capsule)
- H antigen (flagella)
- shiga toxin
- Causes
- Travelers diarrhea (gastroenteritis)
23
Q
Vibrio
A
- Gram positive
- Virulence factors
- Cholera toxin
- adherence to intesintal mucosa
- Causes
- Cholera (ricewater stools)
24
Q
Streptococcus
A
- Gram positve
- S. pyogenes (group A):
- causes:
- Sore throat, scarlet fever, nephritis
- Transmission
- Respiratory droplets
- direct or indirect contact
- causes:
- S. agalactiae (group B)
- Cause
- neonatal sepsis
- Cause
- Virulence factors:
- Streptolysin O and S
- Kill host leukocytes
- Capsules
- attachment
- M protein
- Attachment
- Extracellular enzymes
- break down host molecules
- Strepokinases
- Dissolve clots
- Streptolysin O and S
25
Q
Shigella
A
- Gram negative
- Virulence factors
- Shiga exotoxin
- M cell invasion
- rearrance host actin
- avoid immune system
- Reservoirs
- Humans
- Cause
- Bacillary dysentery (bloody diarrhea)
26
Q
Staphylococcus
A
- Gram Positive
- Virulence factors
- Coagulase
- Exotoxin
- Enterotoxin
- Capsule
- Biofilm
- Drug resistance
- S. aureus in normal flora
- enterotoxin causes TSS
27
Q
Enterobacter
A
- Gram negative
-
UTI and nosocomial infections-
- E. aerogenes