Bacitracin Flashcards
1
Q
Sourse ?
A
Natural
2
Q
Obtain from?
A
Bacillus subtilis
3
Q
Chemically ?
A
Polypeptide
4
Q
Pharmacokinetics ?
A
Use of bactracin is restricted to topical application only
5
Q
Spectrum ?
A
- Gram poaitive cocci
- haemophillus spp
- actinomyces
- neisseria spp
- treponema pallidum
- entero bacteriaceae
6
Q
Mode of action ?
A
Act by inhibition of cell wall synthesis
7
Q
Therapentic use ?
A
Used topically in form of ointments , powders or solutions for treatment of :
1- skin infections ( e.g pyoderma , abcesses )
2- ophthalmic infections ( conjuctiva , cornea )
8
Q
Dose of bacitracin ?
A
Application for 2 to 3 times daily
9
Q
Adverse effects ?
A
- serious nephrotoxicity
- hypersensitivity reaction ( allergy , urticaria )
