Bac/Vanc/Dapt/Fos/Cyclo/PolyB Flashcards by Cody Sellers | Brainscape

Q

Bacitracin

A

Inhibits cell wal- formation
Gram +
Topical ointment
AE: Nephrotoxicity

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Vancomycin

A

Tricyclics glycopeptide inhibits cell wall synthesis
Gram +; MRSA; PRPneumococci
Limited to serious infections
Slow Parenteral: Systemic Gram + infections
Oral: C. Dif
Resistance —> Plasmid mediated chances in permeability or binding
AE: Fever, Chills, Ototoxicity, Flushing, Shock

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Daptomycin

A

Bind/disrupt cell membrane -> Depolarization
Narrow Spectrum Gram +
MRSA, VRSA, Strep Pyogenes, Enterococcus (VRE)
inactivated by surfactant
AE: Renal failure, GI upset, Jaundice

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Fosfomycin

A

Inhibit Cell wall synthesis
Gram + and -:E. Coli, Enterococcus
UTIs

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Cycloserine

A

Inhibit cell wall synthesis; D-Alanine analog
Active against many Gram +/-
2nd line TB
Enters CSF
AE: CNA Toxicity, Peripheral Neuropathy

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

PolyMyxin B

A

Binds/disrupt cell membrane
Gram - Bactericidal Rods: Pseudomonas, E. Coli, EnteroBacter, Haem, Kleb, Shigella,
Topical application; Parenteral for UTI + Bacteremia
AE: Nephrotoxicity, Neurotoxocity

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Νeosporin

A

Polymyxin B + Bacitracin + Neomycin

How well did you know this?

1

Not at all

2

3

4

5

Perfectly