B7-050 Delirium, Attention, and Executive Function Flashcards
contrast gaze preference and gaze palsy
preference: you could get them to have a normal VOR but they only voluntary look one direction
palsy: inability to look to one side, cannot be overcome on VOR
gaze preference indicates a lesion where?
frontal eye fields
(will look away from paralyzed limb)
gaze palsy indicates a lesion where?
PPRF
(will look toward paralyzed side)
where are the frontal eye fields?
dorsolateral prefrontal cortex
disturbance in level of awareness and reduced ability to direct, focus, sustain, and shift attention
delirium
delirium develops over […] and fluctuates in severity
short period (hours to days)
nearly always, delirium is caused by […] process
diffuse toxic metabolic process
(but not severe enough to cause stupor or coma)
which hemisphere is more important to attention?
non-dominant
a non-dominant hemisphere lesion can cause […] neglect
severe
(example where he talked about patient not recognizing own arm; dominant side lesions cause minimal neglect)
non-dominant parietal lobe lesion can cause […] from double simultaneous stimulation
extinction
(can’t recognize the bilateral stimulation)
acquired, chronic disorder affecting multiple cognitive domains
dementia
dementia generally does not affect […] or […] until late in disease course
attention
consciousness
(exception: diffuse lewy body disease)
antibiotic that can cause myoclonic jerks and delirium
cefepime
the conscious executive center of the brain
dorsolateral prefrontal cortex
non-declarative memory is unconscious motor memory that occurs in the […]
striatum and cerebellum
inability to recognize faces
still have emotional response
prosopaganosia
prosopaganoisa occurs due to a lesion where?
inferior temporal cortex (associated with Alzheimers)
has to be bilateral
able to recognize faces
but have no emotional response
capgras syndrome
(results in delusion that loved ones have been replaced by a look-alike imposter)
can be caused by lesions in non-dominant hemisphere
[…] hemisphere of the brain constructs explanations in order to make sense of the world
can even go so far as to confabulate
dominant
(left brain interpreter)
executive centers [4]
amygdala
orbitofrontal cortex
dorsolateral prefrontal cortex
anterior cingulate cortex
subconscious evaluator of the meaning of stimuli
provides emotional response to the consequences of the situation
amygdala
some innate fears (like spiders or snakes) are hardwired in the
amygdala
the […] is involved when we make decisions based on the reward value of stimuli
amygdala
most common cause of bilateral damage to the amygdala
herpes encephalitis
(develop syndrome where they have no reaction to fearful stimuli)