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M&M Test 1 > B6-002 Arthritis > Flashcards

B6-002 Arthritis Flashcards

1
Q

arthritis without positive rheumatoid factor

A

seronegative spondyloarthritis

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2
Q

seronegative spondyloarthritis has a strong association with HLA[..]

A

B27

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3
Q

-asymmetric and patchy involvement
-may have associate skin/nail lesions

A

psoriatic arthritis

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4
Q

psoriatic arthritis is associated with a […] deformity of DIP on Xray

A

pencil-in-cup

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5
Q

symmetric involvement of the spine and sacroiliac joints

A

ankylosing spondylitis

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6
Q

associated with joint fusion, uveitis, and aortic regurgitation

A

ankylosing spondylitis

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7
Q

characteristic Xray finding of ankylosing spondylitis

A

bamboo spine

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8
Q

costovertebral and costosternal ankylosis may cause restrictive lung disease

A

ankylosing spondylitis

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9
Q

associated with Crohn’s or ulcerative colitis

A

inflammatory bowel disease

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10
Q

classic triad of reactive arthritis

A

conjunctivitis
urethritis
arthritis

**can’t see, can’t pee, can’t bend my knee

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11
Q

reactive arthritis is commonly associated with what pathogens? [6]

A

Shigella
Campylobacter
E. Coli
Salmonella
Chlamydia
Yersinia

**She Caught Every Student Cheating Yesterday and overREACTed

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12
Q

inflammatory arthritis
enthesitis
uveitis

A

reactive arthritis

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13
Q

if a patient is unresponsive to NSAIDs and prednisone, what is the next best step?

A

immunosuppressants

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14
Q

inhibits CD20

A

rituximab

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15
Q

inhibits CD80/86

A

abatacept

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16
Q

inhibits IL-6

A

tocilizumab

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17
Q

abdominal pain with findings of blood in stool

A

inflammatory bowel disease

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18
Q

best step to aid in diagnosis of IBD related arthritis?

A

colonoscopy

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19
Q

rates of association of HLAB27 are highest with [2]

A

ankylosing spondylitis
reactive arthritis

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20
Q

best test for psoriatic arthritis

A

CRP

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21
Q

if you can only get one test done on the synovial fluid aspirate, get [..]

A

culture

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22
Q
A

rheumatoid arthritis

**erosive changes to metacarpal head

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23
Q
A

psoriatic arthritis

**pencil in cup changes and DIP involvement

24
Q

aortic regurgitation
(diastolic murmur at right sternal border)

A

reactive arthritis

and ankylosing spondy

25
painless ulcers of the glans penis
circinate balanitis **reactive arthritis
26
chalky deposition which can intermittently drain at first MTP
gout
27
rubbery nodule on extensor surface
rheumatoid nodule
28
skin involvement of gonorrhea
pustules
29
C. dif can cause
reactive arthritis
30
activated as a result of unfolded proteins
IL-17
31
IL17 inhibition can be used to treat [2]
ankylosing spondylitis psoriatic arthritis
32
typically preceded by GI/GU infection 1-4 weeks earlier
reactive arthritis
33
classic triad of reactive arthritis
arthritis, conjuctivitis, urethritis
34
most common infections associated with reactive arthritis [2]
chlamydia c. dif
35
mucocutaneous manifestations of reactive arthritis [2]
-circinate balanitis -psoriaform lesions
36
cardiac manifestation of reactive arthritis
aortic regurgitation
37
the only case where antibiotics are treatment for reactive arthritis is
chlamydia
38
if synovial fluid WBC is less than 2000, think
noninflammatory ** OA, mechanical injury
39
if synovial fluid WBC is greater than 2000,
inflammatory
40
if testing for gonorhhea, you have to
call lab. it requires a different culture medium
41
most common cause of inflammatory arthritis in young adult males
reactive arthritis
42
rates of [....] association are higher in patients that require hospitalization
HLAB27
43
theories related to HLAB27 [4]
-arthritogenic peptide -molecular mimicry -free heavy chain -unfolded protein
44
prior to administered corticosteroids, you should ensure there is not
active infection
45
about 15-20% of people with reactive arthritis will develop
chronic, persistent arthritis
46
treatment options for reactive arthritis that has progressed to chronic arthritis [3]
-sulfasalazine -methotrexate -TNF inhibitors **similar to RA
47
RA spares the [...] back
lower
48
sacroiliac joints and spine most prominently affected
ankylosing spondylitis
49
over 90% of individuals with ankylosing spondylitis are [...] positive
HLAB27
50
DIP involvement with pencil-in-cup deformity
psoriatic arthritis
51
IL-17 and IL-23 inhibitors work through the [...] that is associated with HLAB27
unfolded protein response
52
HLADR4 is associated with
rheumatoid arthritis
53
has migratory joint involvement
gonococcal arthritis
54
tenosynovitis urethritis pustules on skin
gonococcal arthritis
55
is culture positive
gonococcal arthritis

M&M Test 1 (15 decks)

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