B5 HEALTH AND DISEASE Flashcards
Physical health
being free from disease, active, fit, sleeping well and no substance abuse
mental health
feeling good about yourself and being free of conditions such as depression and anxiety
social health
having healthy relationships, loving and being loved
WHO
World health organisation - part of the UN responsible for monitoring global health
Disease
any problem with the body not caused by injury
communicable diseases
diseases caused by pathogens, can be passed on
non communicable diseases
diseases caused by genes or lifestyle. cannot be passed on
correlated diseases
getting one disease increases your chance of another due to diseases weakening organ systems, damaged immune system, weaker defences
genetic disorders
disease caused by inheriting faulty genes from your parents
malnutrition
diseases caused by poor diet
anaemia
lack of iron. causes fewer and smaller red blood cells and low energy
kwashiorkor
lack of protein. swollen belly, small muscles, stunted growth
rickets
lack of calcium or vitamin D Causes weak bones leading to blowed legs
scurvy
lack of vitamin C swollen bleeding gums, muscle and joint pain, lack of energy
ethanol
the drug found in all alcoholic drinks
drugs
chemicals that change the way your mind and body works
cirrhosis
a fatal liver disease caused by drinking too much alcohol over a long period of time
social problems of alcohol
missed work days, increased risk of diseases, risky sexual behaviour, increased violence
obesity
being overweight to the extent that your health is at risk
BMI
body mass index, 30= obese
BMI calculation
BMI = mass (kg) / height2 (M2)
Problems with BMI
someone with a lot of muscle could have high BMI without being obese
Waist ; hip ratio
the ratio of waist to hip width. Over 0.9 (women) or 1.0 (men) = obese
Calculating waist : hip ratio
Waist: hip ratio
= waist width/ hip width
Cardiovascular disease
Harmful substances in blood build up in the arteries around the heart. Blockages can form leading to heart attacks
Stents
Used to treat cardiovascular disease. A tube of metal mesh is fed into the narrowed artery and opened up holding the artery open
Treasuring heart disease with life style
More exercise and a better diet can treat cardiovascular disease. But this takes time
Pathogen
Microorganism that causes disease
Types of pathogens
Bacteria
Virus
Protist
Fungi
Tuberculosis
Bacteria. Serious lung damage , bloody cough, fever
Cholera
Bacteria
Sever life threatening diarrhoea
Chalara ash dieback
Fungi. Kills the leaves of ash trees, killing the tree
Malaria
Protist
Sickness , fever and weakness
Haemorrhagic fever
Virus eg Ebola
Liver and kidney damage
Internal bleeding
HIV
Human immunodeficiency virus attacks white blood cells, causing aids
AIDS
Acquired immunodeficiency syndrome
Weakened immune system making simple infections deadly. Caused by HIV
Opportunistic
Pathogens
Pathogens that in us causing no harm but become dangerous when given the opportunity such as
Helicobateria pylori which cause stomach ulcers
Airborne
Spreading through the the air such as colds and flu in infected droplets of saliva , and chalara ash dieback by fungal spores
Water one
spreading through contaminated water such as chole
Oral route
Eating food contaminated with a pathogen.
Vectors
Animals that spread pathogens in their bites such as malaria that is spread by mosquitoes
Blood fluids
Spreading through contact with infected body fluids such as blood or semen for explain HIV
Chemical defences
Kill pathogens before they can infect us
Lysozyme
Enzyme found in mucus tears and sweat that kills some bacteria
Hydrochloric
Found in the stomach, kills most bacteria on food
Physical barriers
Blood or trap pathogens so they can’t enter the body
Mucus
Sticky substance in most boby openings that traps pathogens
Ciliated cells
Have hairs that sweep mucus up and out of the body
Skin as a physical barrier
Blocks pathogens from entering
STIS
Sexually transmitted infections
Pathogens spread through sexual activity
Preventing STIS
Use barrier contraception (such as condoms) to prevent mixing of fluids (semen, vaginal lubrication, blood).
Screening for STIS
Large scale testing of people to check if they have an STI so they can be treated. This helps to reduce the spread of STIS
Immune system
Destroys pathogens that manage to infect us
Primary immune response
How the body responds the first time it meets a new pathogen
Antigens
Chemical markers on the surface of pathogens (and other cells) that identify them as a pathogen
Antigens are unique to each pathogen
Lymphocyte
White blood cells that produce antibodies. Each lymphocyte makes a different antibody
Antibodies
Chemicals with a specific shape that can stick to the antigens on a pathogen and kill it
Activated lymphocyte
When an antigen sticks to an antibody it activates the lymphocyte causing it to make many copies of itself that make the same antibodies
Memory lymphocyte
Lymphocytes left over after an infection that retain the ability to fight the pathogen
Immunity
When the body has the memory lymphocytes to fight a pathogen. So it can’t be harmed by it
Vaccine
A weakened version of a pathogen that trains the body to fight it without causing disease
How vaccines work
Vaccines are harmless versions of pathogen that still have the antibodies on them, so the immune response is triggered without any risk of disease
Vaccine safety
Vaccines are safe preventing about 6 million deaths per year
Antibiotics
Substance that kill bacteria without harming human cells
Now antibiotics work
They inhibit (stop) an enzyme that maintains bacterial cell walks This kills the bacteria
Resistance
Widespread use of antibiotics has led to resistance meaning many antibiotics don’t work as well as they once did
Drug development
Developing new medicines involves many stages that take of time and money
Discovery phase
Developing new chemicals that might work as medicines
Preclinical testing
Testing on cells grown in the lab or on animals to see if the chemical has any useful effect
Small clinical trial
Testing a few healthy people to check for safety
Large clinical trial
Testing on many patients to diviner how effective the drug is determine the dose
Side effects
Unwanted effects of the medication, that can be quite harmful