B1.2 (Proteins) Flashcards
Proteins
complex macromolecules composed of one or more chains of aminoacids
Amino acids
monomers that make up proetins
Components of a protein
- Amino Group
- Side chain (alpha carbon & R)
- Carboxyl Group
Formation of a peptide Bond
-COOH + -NH2 –> OC-NH + H20
Definition
Non Essential AA
can be produced by body
Definition
Essentials AA
cannot be produced by body
Examples
9 Essential AA
Histidine, Isoleucine, Lysine, leucine, Methionine, Phenylalamine, Threonine, Tryptophan and Vanine
Sources of protein
beans, lentils, meat, nuts, seeds
Uses of proteins
- growth
- repair
- catalyst
- structure (collagen)
- transport (across membrane)
- immunity
- bidning sites for neurotransmitters
- homeostasis (insulin)
Transcription
Dna -> mRna
Translation
mRna -> sequence of AA
Amount of Codons
64 Codons code for 20 AA
Codons
Three adjacent nucleotides in DNA or mRNA that code for a particular AA
Degenerate
Refers to the redundancy of genetic code (multiple codons code for the same protein)
Silent Mutations
Change in DNA sequence that does not result in the change of AA sequence of a protein
Nonesense mutation
A change in DNA sequence in which a stop codon is produced, ending the protein synthesis
Missense Mutation
Change in DNA arrengement as one nucleotide base is swapped causing a diferent AA sequnece
Frameshift Mutation
A change in DNA sequnece in which a nucletide is added or deleted resulting in triplet codons being read incorrectly
Polypeptides
A chain of AA which is linked together by peptide bonds
Lysozyme
enzyme that functions as a natural defense against bacterial infections by breaking down bacterial walls
Where is Lysozyme found
Salive and Tears
Alpha Neurotoxin
Binds to and inhibits receptors causing neuro toxic effects like paralysis and death
where is alpha neurotoxin found
snake venom
Glucagon
hormone which regulates blood sugar (low -> high)