Autonomic Regulation of the Heart - Quiz 1 Flashcards
role of SA node on actions on the heart
- changes nodal action potential
- changes heart rate
parasympathetic role on heart rate
- decreases heart rate
sympathetic role on heart rate
- increases heart rate
sympathetic role on contractility
- increases contractility
sympathetic role on vasculature
- constricts smooth muscle of blood vessels
autonomic role of baroreceptor reflex
- regulates autonomic response to changes in pressure and volume in the vasculature
NE or EPI binds to
- beta1 adrenergic receptors on SA nodal cells
beta receptors on SA nodal cells have what kind of receptor
- G protein coupled receptor
NE or EPI binding to B1 adrenergic receptor causes what?
- increases open state probability of HCN (mostly Na+) - due to cAMP
- increases opening of T type Ca channels - due to more negative membrane potential
- increases opening of L-type Ca channels - due to cAMP -> PKA which opens DHP
opening of HCN and T-type Ca channels causes
- faster rate of phase 4 depolarization
- major effect
opening of L-type Ca channels causes
- less positive threshold
additional sympathetic effect of NE or EPI binding to B1 adrenergic receptor
- increased conduction velocity of action potentials
- increased heart rate
increased conduction velocity of action potentials is what kind of effect
- positive dromotropic
increased heart rate is what kind of effect
- positive chronotropic
parasympathetic effect Ach binds to
- muscarinic receptors