ANS Anatomy Flashcards
Nervous System divided into
- CNS
- PNS
CNS composed of
- brain and spinal cord
PNS composed of
- afferent division
- efferent division
afferent division composed of
- somatic sensory
- visceral sensory
- special sensory
efferent devision composed of
- somatic motor
- autonomic motor
autonomic motor composed of
- sympathetic
- parasympathetic
- enteric
enteric division of ANS
- GI tract nervous system
somatic division organization
- single neuron between CNS and skeletal muscle
somatic innervates
- skeletal muscle at NMJ
somatic (excitatory/inhibitory)
- muscle excitation only
autonomic organization
- two neuron chain connected by ganglion synapse
- preganglionic and post ganglionic neuron
autonomic innervates
- smooth and cardiac muscle
- glands
- GI neurons
autonomic (excitatory/inhibitory)
- excitatory or inhibitory
somatic motor neurons are located in
- spinal cord
- cranial nerve motor nuclei
synapses for somatic motor neurons are located where
- neuromuscular junction
definition of ganglia
- collection of neuronal cell bodies outside CNS
ANS where is the post ganglionic cell body located
- within the ganglion
- or within chromaffin cells of adrenal medulla
chromaffin cells of adrenal medulla are
- modified post ganglionic sympathetic neurons
long postganglionic sympathetic fibers lead from the sympathetic chain to the target organ where they are terminated with
- varicosities
importance of varicosites
- release neurotransmitters over large surface area of the tissue
parasympathetic effect on pupil
- constricts pupil
parasympathetic effect on lacrimal gland
- stimulates tear production and salivation
parasympathetic effect on lungs
- constricts airways
parasympathetic effect on heart
- slows heartbeat
parasympathetic effect on gallbladder
parasympathetic effect on liver
- stimulates contraction for bile release
- glycogen synthesis for glucose storage
parasympathetic effect on stomach
- stimulates digestion
parasympathetic effect on pancreas and GI
- stimulates secretion of enzymes and insulin
parasympathetic effect on GU system
- promotes voiding
- stimulates erection in males
- blood flow for lubrication in women
preganglionic neurons of the Parasympathetic division is called
- craniosacral
axon size of preganglionic neurons in parasympathetic
- long axons
axon size of post ganglionic neurons in parasympathetic
why?
- shorter axons
- ganglia located near target
parasympathetic cell bodies are located in
- brainstem - cranial nerve nuclei
- sacral spinal cord - intermediolateral nucleus
axons in parasympathetic ANS leave brainstem from cell bodies and form
- form parts of cranial nerves
axons in parasympathetic ANS leave sacral spinal cord from cell bodies and leave
- leave through ventral roots
parasympathetic ANS preganglionic axons synapse
- synapse at ganglia
parasympathetic ANS postganglionic axons synapse
- synapse on target organs
sympathetic effect on pupil
- dilates pupil
sympathetic effect on lungs
- relaxes airway
sympathetic effect on blood vessel
- constricts blood vessel
sympathetic effect on heart
- accelerates heartbeat
sympathetic effect on sweat production
- stimulates sweat production
sympathetic effect on small intestine
- inhibits secretion
sympathetic effect on adrenal medulla
- stimulates secretion of NE and EPI
sympathetic effect on GU system
- inhibits voiding
- stimulates orgasm
- stimulates ejaculation
sympathetic division preganglionic cell bodies located
- thoraco-lumbar
- thoracic & upper lumbar
cell bodies of sympathetic division located in
- intermediolaterial column
axons of sympathetic division exit via
- ventral roots
sympathetic preganglionic axons synapse on
- sympathetic chain ganglia
- prevertebral ganglion neurons
- adrenal medulla chromaffin cells
sympathetic preganglionic axons synapse on sympathetic chain ganglia at what level?
- same level
- higher
- lower
how do sympathetic preganglionic axons synapse on the prevertebral ganglion neurons?
- pass through paravertebral sympathetic trunk
size of preganglionic axons of sympathetic division
- preganglionic axons are shorter
size of postganglionic axons of sympathetic division
- postganglionic axons are longer
postganglionic cell bodies adjacent to each thoracic and upper lumbar segment and the cervical and sacral segments are called
pairing of these
- paravertebral ganglia
- paired on either side of the spinal cord
ganglia in front of the vertebral column are called
- pairing of these
- prevertebral ganglia
- collateral ganglia
- preaortic ganglia
- most are not paired
sympathetic chain/sympathetic trunk includes
- ganglia adjacent to thoracic and upper lumbar segment, and cervical and sacral segments
- ganglia in front of the vertebral column
sympathetic chain ganglia are located
- on either side of the vertebral column
cervical ganglia division
- superior
- middle
- inferior
prevertebral ganglia division
- celiac
- superior mesenteric
- inferior mesenteric
sympathetic division called
- sympatho-adrenal
sympathetic preganglionic neuron located
- thoracic spinal cord
adrenal medulla in sympathetic division has control over
- sympathetic control over endocrine function
- release EPI and NE into general circulation
sympathetic preganglionic neurons synapse on
- chromaffin cells
all preganglionic (parasympathetic and sympathetic) neurons release ____ at their synapse on postganglionic neurons
on what kind of receptor
- acetylcholine
- nicotinic
parasympathetic postganglionic neurons release ______ at their synapses on effector tissues
on what kind of receptor
- acetylcholine
- muscarinic (M2 and M2)
sympathetic postganglionic neurons generally release ______ at their synapses on effector tissues
what kind of receptor
- norepinephrine
- adrenergic (alpha 1 and 2, beta 1 and 2)
M2 receptors used for
- SA/AV node cell and cardiac muscle
alpha 1 receptors located on
- used for
- peripheral blood vessels
- vasoconstriction
beta 1 receptors located on
- used for
- SA/AV node cells and cardiac muscle
- increase heart rate
amount of beta 1 versus beta 2 receptors on cardiomyocytes
result
- much more beta 1 than beta 2
- increases contractility
use of beta 2 receptors
- bronchodilation and vasodilation
most of the effects of the alpha 2 receptors results from
- its location on the presynaptic neuron terminal
presynaptic role of alpha 2
- mechanism
- inhibits release of NE from presynaptic neuron so blocks sympathetic signals
- NE feedbacks to alpha 2 receptor and inhibits calcium channel opening
- inhibiting calcium channel opening stops NE release
postsynaptic role of alpha 2
- induces smooth muscle contraction
sympathetic post synaptic neuron releases NE on which receptors
- alpha 1
- alpha 2
- beta 1
sympathetic post synaptic neurons releases Epi on which receptors
- alpha 1,2
- beta 1,2
sympathetic neurons synapsing on renal vasculature and smooth muscle release what neurotransmitter?
on what receptor
- dopamine
- D1
sweat glands are part of what pathway
- innervated by
- sympathetic pathway
- innervated by cholinergic fibers
does the parasympathetic division innervate blood vessels or structures in the skin?
- no
mass discharge of parasympathetic division
- no mass discharge
control by parasympathetic division
- very discrete control of individual effectors
- each organ can be regulated separately
mass discharge of sympathetic division
- capable of mass discharge
- activation of multiple organ systems are once
sympathetic control of skin and digestive tract
- inhibits blood flow to skin
- inhibits digestive tract activity
things only controlled by the sympathetic system
- sweat glands
- pilomotor muscles of skin
- arterioles
- veins
epocrine sweat glands located
- all over the body
epocrine sweat glands function
- thermoregulation
epocrine sweat glands post ganglionic neurons release
- binds to
- Ach
- muscarinic receptor
appocrine sweat glands located
- armpits
- genitals
- perianal
appocrine sweat glands active when
- puberty onward
appocrine sweat glands receptors
- adrenergic receptors
how are appocrine sweat glands regulated?
- hormonally
- EPI in the blood stream
parasympathetic muscles controlling micturition
- detrussor
- internal urethral sphincter
- external urethral sphincter
detrussor is what kind of muscle
- smooth muscle
internal urethras sphincter is what kind of muscle
- smooth muscle
external urethral sphincter muscle is what kind of muscle
- skeletal muscle
detrussor muscle under what kind of control
- does what
- parasympathetic
- contracts
detrussor muscle innervation during filling
- inhibited
detrussor muscle innervation during micturition
- stimulated
internal urethral sphincter under what control
- does what
- sympathetic
- contracts
internal urethral sphincter innervation during filling
- stimulated
internal urethral sphincter innervation during micturition
- inhibited
external urethral sphincter under what control
- does what?
- somatic motor
- causes contraction
external urethral sphincter innervation during filling
- stimulated
external urethral sphincter innervation during micturition
- inhibited
sympathetic effect on skeletal muscle
- very little effect
reflex definition
- involuntary response to a stimulus
cerebral cortex involvement in reflex
- not directly involved
reflex arc can be
- neural
- hormonal
reflex arc pathway
- afferent limb
- central integration enter
- efferent limb
- effector
- functional changes
afferent limb
- sensory limb
efferent limb
- output
functional changes provide
- negative feedback
baroreceptor reflex
- helps maintain blood pressure and volume