ANS Pharmacology

Question 1

prazosin, terazosin, doxazosin target role

Answer 1

• alpha 1 - antagonist

Question 2

sympathetic function

Answer 2

• stimulates smooth muscle contraction - stimulates smooth muscle relaxation - stimulates SA/AV node depolarization

Question 3

M3 receptor role

Answer 3

• secretion - smooth muscle contraction

Question 4

vascular contraction and dilation are regulated normally by which parasympathetic receptors

Answer 4

• none!

Question 5

problems with parasympathetic drugs

Answer 5

• toxicities may be a problem

Question 6

beta 1 antagonist role

Answer 6

• decreased cardiac output

Question 7

sympathetic hormones

Answer 7

• epineprhine - norepinephrine

Question 8

alpha 2 role

Answer 8

• smooth muscle contraction

Question 9

alpha 1 receptor role

Answer 9

• smooth muscle contraction

Question 10

M2 antagonist role

Answer 10

• increased cardiac output

Question 11

route of administration of parasympathetic drugs

Answer 11

• route of admin is key

Question 12

beta 1 role

Answer 12

• SA/AV node depolarization

Question 13

M2 receptor role

Answer 13

• inhibits SA/AV node depolarization

Question 14

dobutamine target role

Answer 14

• beta 1 - agonist

Question 15

parasympathetic hormones

Answer 15

• acetylcholine

Question 16

beta 2 agonist vascular drugs

Answer 16

• none

Question 17

M2 agonist drug

Answer 17

• none

Question 18

acetylcholine receptors

Answer 18

• M2 and M3

Question 19

M2 antagonist drugs

Answer 19

• atropine - glycopyrrolate

Question 20

beta 1 antagonist drugs

Answer 20

• metoprolol - atenolol “LOL” WE’RE ANTAGONIST YOU, YOU BETA MALE THINKING YOU’RE #1

Question 21

phenylephrine target role

Answer 21

• alpha 1 - agonist

Question 22

beta 1 agonist roles

Answer 22

• SA/AV node depolarization - increased HR - increased cardiac output

Question 23

beta 1 agonist drugs

Answer 23

• dobutamine - isoproterenol

Question 24

sympathetic receptors

Answer 24

• alpha 1 and 2 - beta 1 and 2

Question 25

dominant sympathetic receptor on the heart role

Answer 25

• beta 1 - increase HR

Question 26

selectivity of parasympathetic drugs

Answer 26

• nonselective for M1-M5

Question 27

beta 2 antagonist vascular drugs

Answer 27

• none

Question 28

parasympathetic function

Answer 28

• stimulates secretion from glands - stimulates smooth muscle contraction - inhibits SA/AV node depolarization

Question 29

beta 2 role

Answer 29

• smooth muscle relaxation

Question 30

vascular contraction and dilation are regulated normally by which sympathetic receptors which cause which one wins?

Answer 30

• alpha 1 - vasoconstriction - increase BP - beta 2 - vasodilation - decrease BP - more alpha 1 than beta 2 so alpha 1 wins

Question 31

dominant parasympathetic receptor on the heart role

Answer 31

• M2 - decrease HR

Question 32

isoproterenol target role

Answer 32

• beta 1, 2, 3 - agonist

Question 33

epinephrine target role

Answer 33

• alpha 1,2 - beta 1,2 - agonist

Question 34

norepinephrine target role

Answer 34

• alpha 1,2 - beta 1,3 - agonist

Question 35

autonomic functions in all organ systems

Answer 35

• secretion - smooth muscle contraction - smooth muscle relaxation - AV/SA node changes in cardiac myocyte

Question 36

M2 agonist role

Answer 36

• SA/AV node hyperpolarization - decreased HR - reduced cardiac output

Question 37

selectivity of sympathetic drugs

Answer 37

• selective for single receptors or a subset of receptors

Question 38

alpha 1 antagonists vascular drugs

Answer 38

• prazosin - terazosin - doxazosin

Question 39

clonidine target role

Answer 39

• alpha 2 presynaptic - agonist