ANS Anatomy Jensen Lecture Flashcards
1
Q
Mean arterial pressure determined by
A
- cardiac output
- systemic vascular resistance
2
Q
cardiac output composed of
A
- heart rate
- stroke volume
3
Q
heart rate also referred to as
A
- automaticity
4
Q
stroke volume referred to as
A
- myocardial contractility
5
Q
systemic vascular resistance referred to as
A
- vascular tone
- smooth muscle contractility
6
Q
two synthetic beta agonists
A
- dobutamine
- isoprotenerol
7
Q
two endogenous beta agonists
A
- NE
- Epi
8
Q
dobutamine affinity for which beta adrenergic receptor
A
- B1 > B2
9
Q
isoproterenol affinity for which beta adrenergic receptor
A
- B1 and B2
10
Q
Beta adrenergic receptor activation pathway
A
- increased cAMP
- increased extracellular Ca2+ entry
- increased intracellular Ca2+ release
- increased contractile force
- increased stroke volume
- increased cardiac output
11
Q
the most important difference between EPI and NE
A
- low affinity of NE for beta 2
12
Q
NE effect on arterial resistance
A
- increases arterial resistance
- only acts on alpha 1
13
Q
EPI effect on arterial resistance
A
- mixed effect on resistance
- acts on alpha 1 and beta 2
14
Q
HCN channel responsive to
A
- cAMP activity
- increase influx of Na+
- increases phase 4 depolarization
15
Q
PKA targets
A
- DHP channel
- makes threshold more negative
