autonomic nervous system. Flashcards
bethanecol
direct muscarinic activator. treatment for ileus and urinary retention.
methacholine
direct muscarinic and nicotinic activator. treatment for bronchial hyperactivity
nicotine
direct nicotinic activator
pilocarpine
direct muscarinic activator. cholinomimetic, causes contraction of the ciliary muscle thus increasing flow to the canal of schlem. also used for xerostomia.
edrophonium
reversible AChE inhibitor. short acting for the diagnosis of myasthenia. also used for the diagnosis of cholinergic crisis from too much neostigmine
physostigmine
reversible AChE inhibitor. used in atropine OD. tertiary amine.
neostigmine
reversible AChE inhibitor. treatment for myasthenia gravis. increases the amount of Ach in the synapse.
echothiaophate
irreversible AChE inhibitor. this is an organophosphate which is used in glaucoma
malathion
irreversible AChE inhibitor
parathion
irreversible AChE inhibitor
atropine
muscarinic blocker. antispasmotic, antisecretory, management of AChEi OD. antidiarrheal.
benztropine
muscarinic blocker. lipid soluble used for parkinsons treatment
ipratropium
muscarinic blocker. asthma and COPD. no CNS entry. reduces the volume of secretion.
scopolamine
muscarinic blocker. motion sickness and causes short term memory loss.
hexmethonium
ganglionic blocker. blocks all autonomic functions
mecamylamine
ganglionic blocker. blocks all autonomic functions
phenylephrine
alpha 1 agonist
methoxamine
alpha 1 agonist
clonidine
alpha 2 agonist
methyldopa
alpha 2 agonist
isoproteranol
nonselective beta agonist. note this will lower the blood pressure because it has no affinity to the alpha receptors.
dobutamine
nonselective beta agonist (1 > 2)
albuterol
beta 2 agonist
ritodrine
beta 2 agonist
terbutamine
beta 2 agonist
salmeterol
beta 2 agonist
epinephrine
hits all of them. beta 1, 2, alpha 1, 2
norepinephrine
beta 1, alpha 1, 2
amphetamine
indirect-acting adrenergic receptor agonists
cocaine
indirect-acting adrenergic receptor agonists
ephedrine
indirect-acting adrenergic receptor agonists
tyramine
indirect-acting adrenergic receptor agonists
doxazosin
alpha 1 antagonist
prazosin
alpha 1 antagonist
terazosin
alpha 1 antagonist
yohimbine
alpha 2 antagonist
mirtazapine
alpha 2 antagonist
phenoxybenzamine
mixed alpha antagonist
phentolamine
mixed alpha antagonist
acebutolol
beta 1 antagonists
atenolol
beta 1 antagonists
metoprolol
beta 1 antagonists
pindolol
nonselective beta antagonist
propanolol
nonselective beta antagonist
timolol
nonselective beta antagonist. used in glaucoma. blocks the action of norepi at the ciliary epithelium. decreases aqueous humor formation