Asthma Flashcards

1
Q

What are the aetiologies of asthma?

A

Atopy and allergy
Genetics
Environmental factors
Drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the pathophysiology of asthma?

A

Disease of the lung airway

Airway inflammation mediation by immune system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the symptoms of asthma?

A
Wheeze
SOB 
Chest tightness
Cough
Occasional sputum
Evidence of variable symptoms
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are some past medical history indicators of asthma?

A

Childhood asthma
Bronchitis
Eczema
Hayfever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the essential investigations for asthma?

A
Evidence of airflow obstruction and variability
SPIROMETRY - less than 0.7 ratio
PEFR - variability
CO TRANSFER TEST
RESPONSE TO ICS and BRONCHODILATORS
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are useful investigations?

A

CHEST XRAY
FBC
SKIN PRICK TESTS
TOTAL IGE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the 1st step of management in adults?

A

Inhaled SABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the 2nd step in adults?

A

Add inhaled corticosteroids of dose 200-800micrograms
If using SABA 3x a week, waking one night a week, sub-normal exercise tolerance, steroids for exacerbation in past 2 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the 3rd step in adults?

A

Add LABA and assess control
If good control then continue
If benefit but not adequate control then continue and increase ICS dose to 800
If no response, stop LABA and increase steroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the 4th step in adults?

A

Increasing steroid up to 2000micrograms per day

Consider trial of leukotrine receptor antagonist or SR theophylline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the 5th step in adults?

A

Use a daily steroid table
Maintain high dose ICS
Refer to specialist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is step 1 in children?

A

SABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is step 2 in children?

A

ICS 200-400 micrograms or LTRA in under 5a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is step 3 in children?

A

LABA as in adults

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is step 4 in under 5s?

A

Refer for confirmation of diagnosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is step 4 in 5-12s?

A

Increase ICS up to 800micrograms daily

17
Q

What is step 5 in 5-12s?

A

Daily steroid tablet
Maintain high dose ICS
Refer to specialist

18
Q

What is SANE?

A
Used to measure asthma control in children
SABA/week
Absence from school/week
Nocturnal symptoms/week
Excertional symptoms/week