Ascending and descending tracts Flashcards
what are the different type of axon fibres from skin
Aa (alpha)
Ab (beta)
Ad (gamma)
C
Describe the diameter, speed, myelination and sensory receptors for Aa fibres
Diameter (nanometre): 13-20
Speed (m/sec): 80-120
Myelinated: very fast
Sensory receptors: proprioceptors of skeletal muscle
Describe the diameter, speed, myelination and sensory receptors for Ab fibres
Diameter (nanometre): 6-12
Speed (m/sec): 35-75
Myelinated: slower speed than Aa but faster than Ad
Sensory receptors: mechanoreceptors of skin
Describe the diameter, speed, myelination and sensory receptors for Ad fibres
Diameter (nanometre): 1-5
Speed (m/sec): 5-30
Myelinated: slower speed than Aa and Ab
Sensory receptors: pain, temperature
Describe the diameter, speed, myelination and sensory receptors for C fibres
Diameter (nanometre): 0.2-1.5
Speed (m/sec): 0.5-2
NOT Myelinated: slowest
Sensory receptors: Temperature, pain and itch
what type of neurons are sensory neurons
Unipolar neuron
see pic online
Describe the pain fibre input
- Painful stimulus on skin (needle prick)
- AP released that travels along the sensory neuron with Ad or C fibre axon
- AP reaches the SUPERFICIAL dorsal horn of the spinal cord
Describe the touch fibre input
- Touch stimulus on skin (touching dots)
- AP released that travels along the sensory neuron with Ab fibre
- AP reaches DEEP dorsal horn of the spinal cord
Explain DAVE
Dorsal root
Afferent (sensory info arrives into spinal cord)
Ventral root
Efferent (motor info exits out of spinal cord)
what are ascending and descending tracts
Tracts of myelinated axons- forms spinal cord white matter
Ascending- carries sensory info from periphery to brain
Descending- carries motor info from brain to spinal cord
what are the two types of ascending tracts
- Discriminative (fine) touch- feather touching foot
Dorsal column pathway - Pain
Spinothalamic pathway
How does the info in sensory pathways travel
1st neuron- Primary sensory neuron (periphery-takes info from mechanoreceptors)
2nd neuron- Secondary sensory neuron (spinal cord/brainstem)
3rd neuron- Tertiary sensory neuron (thalamus to cerebral cortex)
what are the 3 types of TOUCH cutaneous and subcutaneous mechanoreceptors (Ab afferents)
Meissner’s corpuscle
Merkel disk
Hair follicle receptor
what are the 2 types of PRESSURE cutaneous and subcutaneous mechanoreceptors (Ab afferents)
Pacinian corpuscle
Ruffini ending
Describe the dorsal column (descrimininative touch) pathway
- Touch stimulus on skin (touching dots)
- AP released that travels along the sensory neuron with Ab fibre
- AP reaches DEEP dorsal horn of the spinal cord
PRIMARY: - primary afferent signal (same axon) travels in the dorsal column/ funiculus through the lumbar, thoracic and cervical spinal cord.
- in the medulla- the primary afferent neuron synpases into dorsal column nuclei and becomes internal arcuate fibres.
SECONDARY - the internal arcuate fibres cross over to the other side and goes up through the medial lemniscus in the pons and midbrain
- from midbrain the signal goes to the VPL (ventral posterolateral nucleus) of the thalamus
TERTIARY - the signal goes from thalamus to the internal capsule and then to the sensory cortex (info processed here)
what fibre axons are involved in sensing pain
A-delta
C
what are the nociceptor peripheral endings that detects pain
free nerve endings
Describe the spinothalamic pathway
PRIMARY
1. Painful stimulus on skin (needle prick)- detected by free nerve endings
2. AP released that travels along the sensory neuron with Ad or C fibre axon
3. AP reaches the SUPERFICIAL dorsal horn of the spinal cord- primary afferent
SECONDARY
4. The primary afferent signal synapses into the secondary afferent signal and crosses over to the ventro-lateral aspect of the spinal cord.
5. The secondary signal travels through lumbar, thoracic and cervical spinal cord - Anterolateral funiculus
6. The secondary afferent signal travels on the same side and travels upwards through the medulla,pons, midbrain and thalamus.
TERTIARY
7. Thalamus- secondary signal synpases into tertiary signal and travels through internal capsule to the sensory cortex- information processed here
what are the two types of descending tracts? (motor-voluntary)
1) Corticospinal tracts
2) Corticobulbar tracts
How does the info in motor (descending) pathways travel
From Motor Cortex, Upper motor neuron carries info and synpases to lower motor neuron in brainstem/spinal cord. the lower motor neuron carries info the muscle = movement
What is the purpose of corticobulbar pathway
motor control of cranial nerves
Describe the corticobulbar pathway
- AP generated in motor cortex
- Neurons carry AP down midbrain, pons and medulla
- SOme neurons synpase in the trigeminal motor nucleus in pons to become –> Trigeminal NErve
- Some neurons synapse in the facial motor nucleus in pons to become –> Facial nerve
- Some neurons synapse in the nucleus ambiguous in medulla to become –> Vagus nerve and Hypoglossal nerve
Describe the corticospinal pathway
- Motor cortex generates AP
- Neurons travel down Midbrain, pons and medulla and crosses over at pyramidal decussation
- 85% cross over are knowsn as lateral corticospinal and 15% stay on the same side and are known as anterior corticospinal
- both travel downwards
- anterior corticospinal (15%)- stops at mid thoracic level
- lateral corticospinal (85%)- continues travelling downwards
what are the three types of descending tracts? (motor-tone)
Reticulospinal
Tectospinal
Vestibulospinal
Describe the 2 tracts in the reticulospinal pathway (name, origin and their function)
Reticulopsinal pathways are bilateral projections
1) Pontine Tracts
- Comes from ipsilateral oral and caudal PONTINE reticular nuclei
- controls EXTENSORS
2) Medullary Tracts
- comes from ipsilateral gigantocellular reticular nuclei of the MEDULLA
- controls FLEXORS
how does the reticulospinal pathways travel down the spinal cord
- Bilateral projections
- on the ventral surface of spinal cord
- pontine tracts are medial in ventral area of spinal cord
- medullary tracts are lateral in ventral area of spinal cord
- runs entire lenght of spinal cord
Why are reticulospinal pathway important and what does it damage lead to
- Important in maintenace of balance and posture
- modulates acitivty of alpha-motor neurons (LMN)
- damage leads to loss of postural control
describe the vestibulospinal pathway
- runs medially in ventral area- ventromedial
- originates from ipsilateral lateral vestibular nucleus in medulla
- runs entire length of spinal cord
describe the tectospinal pathway
- runs ventromedially
- origin- contralateral superior colliculus in midbrain and crosses
- runs only to cervical spinal cord only and doesnt to thoracic and lumbar
why does the tectospinal pathway project to cervical cord ONLY
- Innervates muscles of the neck ONLY
- modulates activity of both alpha and gamma motor neurons (voluntary and involuntrary)