Approach to Renal Complaint Flashcards
Proteinuria
Protein in the urine
Glucosuria
Glucose in the urine
Hematuria
Blood in the urine
Dysuria
Painful urination
Polyuria
Frequent urination
UTI
Urinary Tract Infection
GFR
Glomerular Filtration Rate
CrCl
Creatine Clearance
AKI
Acute Kidney Injury
CKD
Chronic Kidney Disease
ESRD
End stage renal disease
Uremia
Elevated BUN levels
BUN
Blood Urea Nitrogen
What is and How is urea nitrogen created?
A waste product created when liver breaks down proteins and sends to kidney for excretion
Cr
Creatine
How is creatine created?
Waste product of muscle breakdown that is constantly produced and excreted by kidneys
4 Renal labs
BMP
CMP
Urinalysis
Urine Microscopy
What should the levels of protein, blood, glucose and bilirubin be in the urine?
ZERO
CMP test
A BMP + liver function tests
What is an AKI?
Impairment of renal function that results in retention of waste products that are normally excreted by kidney
If AKI does not resolve in _____ it may progress to ____
3 months
CKD
Is AKI a structural injury to the kidney?
NO
List some risk factors for AKI
Old age CKD Hypertension Diabetes Nephrotoxins (NSAIDS, Antibiotics)
What are the 3 categories of causes for AKI?
- Pre-renal AKI
- Intrinsic AKI
- Post-renal AKI
Pre-Renal AKI
Injury occurring upstream of the kidneys
ex. Hypertension
Intrinsic AKI
Injury occurring at the level of the kidneys
ex. Glomerulonephritis
Post-Renal AKI
Injury occurring downstream of the kidneys
ex. Bladder outlet obstruction
Main physical exam finding for pre-renal AKI?
HISTORY IS IMPORTANT
Fluid loss, volume depletion
- dry tongue, poor skin turgor, hypotension
Renal ROS?
All things urine
- Urine frequency, appearance, painful
Main thing to look at during a renal exam?
Volume status!
- jugular venous pressure (distended?), dry tongue, cap refill, edema
What are the very important labs to obtain on all patients with AKI?
BMP and Urinalysis with urine microscopy
What must be present to diagnose CKD?
FOR AT LEAST 3 MONTHS:
- GFR < 60
- Proteinuria and Abnormal urinary sediment
GFR is less than ___ for CKD
60
If the GFR is less than 60 for less than 3 months what is the diagnosis?
AKI
In absence of _______, stages 1 and 2 of CKD are not enough to diagnose CKD
Kidney damage
As you progress further towards CKD stage 5, what number is dropping?
GFR
List some risk factors for CKD
AKI
Hypertension
Diabetes
Cardiovascular disease (CVD)
Signs and symptoms for CKD are similar to AKI. What are a few extra things to look for?
Pericardial friction rub
Asterixis - wrist thing
Uremic frost
What are the 3 labs to get for CKD patients?
- GFR
- Proteinuria
- Urinalysis with Urine microscopy
GFR is not reliable in patients with?
AKI
Treatment for CKD?
Dialysis
Indications for dialysis?
A - acidosis E - electrolyte disturbance I - ingestion O - volume overload U - uremia
Cystitis
Bladder infection
Pyelonephritis
Kidney infection
How does a UTI occur?
Colonization of urethra or urine with uropathogen
Most common uropathogen with a UTI?
E. Coli
Common causes of UTI
Sexual activity
Outflow obstruction
Fecal contamination
Symptoms of cystitis
Dysuria, urinary frequency
Symptoms of pyelonephritis
Dysuria, urinary frequency, fever, flank pain, nausea
Important lab to order for UTI?
Urine culture
What number should you be looking for with a urine culture?
> 100,000 cfu/mL
What is the gold standard test for pyelonephritis?
Ct scan
Special test for Kidney (pyelonephritis)?
Lloyd’s sign (punch)
Lloyd’s sign
(+) = pain with deep percussion of costovertebral angle
Treatment for UTI/cystitis/pyelonephritis?
Antiobiotics
Nephrolithiasis
Kidney stones
Normally, kidney stones are made of?
Calcium oxalate
Symptoms of nephrolithiasis?
Pain, urinary urgency, dysuria, polyuria
Upper ureter sympathetic innervation
T10-T11
Upper ureter parasympathetic innervation
Vagus
Lower ureter sympathetic innervation
T12-L2
Lower ureter and bladder parasympathetic innervation
S2-S4
Palpable points that are reflections of visceral dysfunction
Chapman’s reflex points
Anterior kidney chapman point
1 inch superior and 1 inch lateral to umbilicus
Anterior bladder chapman point
umbilicus
Posterior kidney chapman point
Lateral to spinous process of L1
Posterior bladder and ureter chapman point
Transverse processes of L2