Apoptosis Vs. Necrosis

Question 1

Quantity of cells dying

Answer 1

• Apoptosis: single
• Necrosis: many

Question 2

membrane activity

Answer 2

• Apoptosis: blebbing w/ apoptotic bodies
• Necrosis: swell & membrane lyses

Question 3

inflamatory response

Answer 3

• Apoptosis: not much
• Necrosis: significant

Question 4

breakdown

Answer 4

• Apoptosis: Tidy phagocytosis
• Necrosis: messy

Question 5

Energy

Answer 5

• Apoptosis: requires ATP
• Necrosis: no ATP needed

Question 6

DNA Compaction

Answer 6

• Apoptosis: DNA compacts
• Necrosis: DNA doesnt compact

Question 7

DNA cleavage

Answer 7

• Apoptosis: non-random (ladder)
• Necrosis: random (smear)