Apoptosis Flashcards
1
Q
Apoptosis
A
A type of cell programmed death
2
Q
Give example of non apoptotic programmed cell death
A
Autophagy and regulated necrosis
3
Q
Apoptosis depends on which protein
A
Caspase
4
Q
How does caspases affect nectoptosis?
A
Caspases provide a negative feedback to it
5
Q
What is the key mediator of necroptosis
A
Receptors interacting protein
6
Q
What is autophagy and how does it work?
A
It is an incharge cellular degradation process of cytoplasmic component through the formation of autophagosome and when it fuses with lysosome it forms autolysosome. Enzymatic breakdown kills the cell.
7
Q
What are the morphological changes that occurs in apoptotic cells?
A
Cell shrinkage, chromatin condensation (pyknosis), nuclear fragmentation (karyorrhexis), plasma membrane blebbing
