APEX: Monitoring I Respiratory Flashcards
CO2 Waveform consistent with obstruction can show
Elevated peak with normal plateau pressure
Conditions associated with elevated peak pressure and normal plateau pressure : ETT
Kinked ETT
Conditions associated with elevated peak and normal plateau pressure : lungs and other
Bronchospasm
Aspiration of foreign body
What is elevated peak pressure and normal plateau pressure indicates?
Reduction in dynamic compliance caused by increased airway resistance.
Assessment of Pulmonary Resistance and compliance: Resistance formula
Resistance = P(airway) - P (alveolar) / Gas flow rate
Defined as the force that acts opposite to the relative motion of an object?
Resistance
What is the definition of compliance?
Change in Volume/ change in pressure
Change in volume for a given changes in pressusre
Compliance
What does compliance measure?
The elastic properties of the lungs and chest wall
What is compliance influenced by? DAMAP
Degree of lung inflation Alveolar surface tension Muscle tone Amount of interstitial lung water Pulmonary fibrosis
What is dynamic compliance?
The compliance of the lungs /chest wall DURING air movement
Dynamic compliance is the pressure
required to inflate the lung to a given volume is a
Static means
Not moving
Static compliance measures
Lung compliance where there is NO AIRFLOW
Static compliance is the pressure
required to keep the lung inflated to a given volume
Static compliance is the function
of the tendency of the lung/chest to collapse. Since there is no airflow during this measurement there is no resistance to overcome
Dynamic compliance is a function of
Function of AIRWAY RESISTANCE and the TENDENCY OF THE LUNG/CHEST WALL to COLLAPSE
The significance of peak inspiratory pressure and plateau pressure
The peak inspiratory and plateau pressure provide key insight to a patient’s airway resistance and LUNG-THORACIC COMPLIANCE
Peak inspiratory Pressure (PIP)
Is the maximum pressure in the patient’s airway during inspiration
What is PIP affected by?
Because air flow is flowing into the airway during inspiration, PIP is affected by airway resistance and lung-thoracic compliance
Dynamic compliance FORMULA
Tidal volume / Peak pressure- PEEP
What is plateau pressure?
the pressure in the small airways and alveoli after the target TV is delivered.
Plateau pressure is the pressure in the small airways and alveoli after the target TV is delivered. Does airway resistance affect plateau pressure? why/why not?
Since there is no airflow at this time, airway resistance does not affect plateau pressure.
Plateau pressure reflects the
elastic recoil of the lungs and thorax during the inspiration pause (no gas i s moving in or out) of the lungs
What is BAROTRAUMA risk is high ?
Risk increases when plateau pressure exceeds 35cm/H2O
What are complications of ELEVATED plateau pressure?
Ventilator-associated lung injury
Pneumothorax
Pneumomediastinum
SC emphysema
IF Barotrauma exists, you should aim to
Reduce plateau pressure by reducing TV, inspiratory flow and PEEP. Sedation is helpful
Static compliance formula
Tidal volume / Plateau pressure - PEEP
In the adult, the normal static compliance is
35-100 ml/cm H2O
In the Child, the normal static compliance is
> 15cm /cm H2O
If PIP is increase and PP increase then: Total complaince has ________or TV has _______
Total compliance has decreased
TV has increased
If PIP is increased and no changed in PP then: Total compliance has________ or TV has _______
Resistance has increase OR Inspiratory flow rate has increased.
Compliance with : Endobronchial intubation?
Decreased
Compliance with : Pulmonary edema
Decreased
Compliance with : Pleural effusion
Decreased
Compliance with : Tension pneumothorax
Decreased
Compliance with : Atelectasis
Decreased
Compliance with : Chest wall edema
Decreased
Compliance with : Abdominal insufflation
Decreased
Compliance with : Ascites
Decreased
Compliance with : Trendelenburg position
Decreased
Compliance with : Inadequate muscle relaxation
Decreased
Increase resistance in airway with
Bronchial secretion
Compression of the airway
ETT cuff HERNIATION
FB aspiration
Phase I (A-B) represents
Exhalation of anatomic dead space (flat before phase II)
Phase II (B-C) represents
Exhalation of anatomic dead space+ ALVEOLAR GAS.
Upstroke is phase
II
Phase III (C-D) represents
exhalation of alveolar gas.
Plateau phase is
III
Phase IV represents
Inspiration of fresh gas that DOES NOT CONTAIN CO2
Illustrated by return of waveform to baseline
Phase IV
Capnography measures
ETCO2 concentration over time.
Capnography measures 3 main things?
Assessment of metabolism
Circulation
Ventilation
CO2 concentration gradient
From the tissues to the breathing circut
What is the final product of aerobic metabolism?
Carbon dioxide
CO2 diffuses airway then from the tissues on, what happen?
from the tissue and enters the venous circulation, From here, the CO determines the rate of transfer towards the lungs. In the lungs, CO2 follows a concentration gradient as it diffuses across the alveolar capillary membrane. Once the CO2 in the alveolus, ventilation is the process by which CO2 is removed from the body
What point in the CO2 waverform is ETCO2 measure?
Point D
Normal ETCO2
35-40 mmHg
The alpha angle is
Airway obstruction reading
Where is the alpha angle measure?
Point C
Normal alpha angle is
100-110 degreers
An increase alpha angle means
EXPIRATORY AIRFLOW OBSTRUCTION such as COPD, bronchospasm or a KINKED ETT TUBE.
Alpha angle is between
the first expiration upstroke and the plateau line
Beta angle is
REBREATHING reading
The beta angle is measure at what point
point D
When the patient inspires, the capnography should immediately
return to zero because fresh gas flow does not contain CO2
The beta angle is increased indicating
Rebreathing
Causes of Rebreathing
Faulty unidirectional valves
Exhausted CO2 absorbent
If Expiratory vale is faulty you will notice 2 things about the waveform
Beta angle become WIDER DURING INSPIRATORY
Baseline does not return to zero
Middle of case expiratory valve malfunction
Increased the FGF to finish case
after, took valve assembly and flipped the disc over
2 Methods of CO2 analysis
Mainstream (in line)
Sidestream (diverting )
In what CO2 analysis methods is the device attached to the ETT
Mainstream (in line)
What CO2 analysis method has a faster response time,
Mainstream , does not require a water trap or pumping mechanism
Benefits mainstream (in line) CO2 analysis
Because it’s attached to the ETT , it does not increase apparatus dead space as well as adds extra weight
Sidestream (diverting) CO2 analysis location
Located outside of the airway
Sidestream uses what kind of mechanism?
A pumping mechanism continuously aspirate the gas sample from the breathing circuit, and for this reason, the response time is slower.
CO2 analysis method with a water trap
Sidestream ; to prevent contamination of the device.
Identify caused of the abnormal waveform if there is a PROLONGED UPSTROKE
Airflow obstruction
Identify caused of the abnormal waveform if there is a INCREASED ALPHA ANGLE
Airflow obstruction
COPD
Bronchospasm
Kinked ETT
Identify caused of the abnormal waveform if there is a CARDIAC OSCILLATION
Heart beating against the lungs
CARDIAC OSCILLATION more common in ? why?
In children, close proximity of heart to the lungs
Identify caused of the abnormal waveform if there is a CURARE CLEFT
Spontaneous breaths during mechanical ventilation
Identify caused of the abnormal waveform if there is a CURARE CLEFT, If presents during spontaneous ventilation , suggests
INADEQUATE MUSCLE RELAXANT (lack of synchronizaiton between intercostal muscles and diaphragm)
Low ETCO2 indicates
Hyperventilation
Decrease CO2 production
Increased alveolar dead space
BP and CO2
Hypotension leads to CO2 production
Elevated ETCO2 with normal plateau?
Make sure you look at the baseline and that it returns to zero. Its not rebreathing. Occurs with increased production of CO2 or DECREASED ALVEOLAR VENTILATION
Baseline not returning to zero is
rebreathing
Inadequate FGF with mapleson circuit lead to
Rebreathing
Widened beta angle
Incompentent unidirectional valve
Patient with single lung transplant and CO2 waverform
Alveolar gas from transplanted lung and the diseased lung have different time constants
The first peak is alveolar GAS FROM TRANSPLANT(normal time constant)
The second peak is alveolar GAS from DISEASED Lung.
Leak in sample time CO2 waveform?
The beginning of the plateau is low, because dilution of alveolar gas at atmospheric air is aspirated into the sample line. NOT SEEN WITH SPONTANEOUS VENTILATION.
Hyperventilation from increased MV lead to this electrolyte imbalance?
Metabolic acidosis
For ETCO2 to be detected, what must be met?
CO2 must be produced during metabolism
Adequate pulmonary blood flow to deliver CO2 to lungs
Adequate VENTILATION to transport CO2 to the breathing circuit
INTACT SAMPLING SYSTEM
When answering question about ETCO2, answer these 2 things
What is the cause?
Does this affect the PaCO2 to ETCO2 gradient?
Causes of changes in ETCO2 can be divided into
Changes in CO2 Production: Impaired pulmonary perfusion, or /and Impaired ventilation
Equipment malfunction
Normal PaCO2 to EtCO2 gradient
2-5 mmHg
A wide PaCO2 to EtCO2 gradient suggests
V/Q mismatch/ OR equipment malfunction
PaCO2 is _____Than EtCO2
Higher
The first thing that should come to mind with wide PaCo2 to EtCO2 gradient
INCREASED DEAD SPACE (such as hypotension, reduced CO / PE etc)
Increase Basic Metabolic RATE ( increase VO2) affect CO2 how ?
Increased CO2 (increased production)
MH affect CO2 how ?
Increased CO2 (increased production)
Thyrotoxicosis affect CO2 how ?
Increased CO2 (increased production)
Fever affect CO2 how ?
Increased CO2 (increased production)
Sepsis affect CO2 how ?
Increased CO2 (increased production)
Seizures affect CO2 how ?
Increased CO2 (increased production)
Laparoscopy affect CO2 how ?
Increased CO2 (increased production)
Tourniquet or vascular clamp removal affect CO2 how ?
Increased CO2 (increased production)
Sodium bicarbonate administration affect CO2 How?
Increased CO2 (increased production)
Anxiety affect CO2 How?
Increased CO2 (increased production)
Pain affect CO2 How?
Increased CO2 (increased production)
Decrease BMR (Vo2) affect CO2 How?
Decreased CO2 production and delivery to the lungs.
Increased anesthetic depth affect CO2 How?
Decreased CO2 production and delivery to the lungs.
Hypothermia affect CO2 how?
Decreased CO2 production and delivery to the lungs.
Decreased pulmonary blood flow affect CO2 how?
Decreased CO2 production and delivery to the lungs.
Decreased cardiac output affect CO2 how?
Decreased CO2 production and delivery to the lungs.
Hypotension affect CO2 how?
Decreased CO2 production and delivery to the lungs.
Pulmonary Embolusm affect CO2 how?
Decreased CO2 production and delivery to the lungs.
V/Q mistmatch affect CO2 how?
Decreased CO2 production and delivery to the lungs.
Medication side effect affect CO2 HOw?
Decreased CO2 production and delivery to the lungs.
Main mechanism of Increased ETCO2
Decreased alveolar ventilation
Decreased alveolar ventilation causes : RESP
Hypoventilation
COPD
Metabolic alkalosis (If spontaneous ventilation)
Decreased alveolar ventilation causes: NEURO
CNS depression
Residual NMB
High spinal
NM disease
Main Cause of DECREASED ETCO2
Increase alveolar ventilation
Increased alveolar ventilation causes : RESP
Hyperventilation
Metabolic acidosis
Can cause either increase or decrease alveolar ventilation
Medication side effect
Inadequate ventilation on alveolar ventilation
Increase Alveolar ventilation
Equipment malfunction that would cause Increased ETCO2
Rebreathing CO2 absorption exhaustion Unidirectional valve malfunciton Leak in breathing circuit Increased apparatus dead space
Equipment malfunction that would cause Decreased ETCO2
Ventilator disconnect Esophageal intubation Poor seal with ETT or LMA Sample line leak Airway obstruction Apnea
The pulse oximeter utilizes which Law
Beer-Lambert Law
Pulse oximeter emits ____
2 wavelenghts of light
Pulse oximeter emits 2 wavelengths of light
oxygenated blood better absorbs near infrared light (940nm)
Deoxygenated blood better absorbs red light (660nm)
What does the pulse oximeter really look at ?
Ration of light absorption during the peak of the waveform relative to the trough of the waverform.
At the peak of the waveform, the
Ratio of arterial blood to venous blood is INCREASED>
The beer-lambert law relates
the intensity of light transmitter through a solution and the concentration of the solute within the solution. in this instance, the solution is blood and the solute is hemoglobin
The oxygen saturation determines
the color of the blood. Comparing the ratio of light absorption in arterial and venous blood.
Red light is preferentially absorbed by
Deoxyhemoglobin (higher in venous blood)
Near infrared light is preferentially absorbed by
Oxyhemoglobin (higher in arterial Blood )
For pulse ox, the amount of light absorbed
Changes throughout the pulse cycle
At the trough of the pulse ox waveform,
There is a greater amount of venous blood in the tissue sample
At the peak of the pulse ox waveform,
There is greater amount of arterial blood in the tissue sample.
SPO2 formulation
Oxygeated Hgb / Oxygenated Hgb + Deoxygenated
x 100%
SPO2 response time, as a general rule
The closer the monitoring site to the central circulation, the faster it will respond to ARTERIAL desaturation.
Central monitoring sites are more resistant to the
vasonconstrictive efrects of SNS stimulation and hypothermia
Sites of SPO2 From MOST to LEAST RESPONSIVE: FAST
Fast = EAR, nose, Tongue, esophagus forehead
Sites of SPO2 From MOST to LEAST RESPONSIVE: Middle
FINGER
Sites of SPO2 From MOST to LEAST RESPONSIVE: SLOW
TOE
When SPO2 is monitored on the head or esophagus,
THE Trendelenburg position can cause venous engorgement resulting in a FALSELY DECREASED SPO2 measurement.
SPO2 90%= PaO2 is ______
60 mmHg
SPO2 80%= PaO2 is ______
50 mmHg
SPO2 70%= PaO2 is ______
40 mmHg
SPO2 monitoring is most useful when the patient’s
PaO2 aligns with the steep portion of the Oxyhemoglobin dissociation curve.
Left shift mean _____affinity
think L “Love to hold” Increased
Right shift mean ______Affinity
Decreased affinity (R for released)
CADET FACES RIGHT
Increased CO2
Acidosis (Increase H+) (decrease pH)
Increased 2,3, DPG
Increased temperature
LEFT shift is associated with
Decreased CO2
Alkalosis (decreased H+) (Increased pH)
Decreased 2,3 DPG
Decreased Tempature
Once the SPO2 reaching 100% on the plateau portion of the curve, you are no longer able to extrapolate the PaO2; it could be
100 or 500mmHg, either way the SPO2, will read 100%
5 Methods to improve the SPO2 signal
Performance of a digital block Warming the extremity Protecting the extremity from light Vasodilating crea Administer an arterial vasodilator.
Pulse oximeter is a useful monitor of
Vascular compression
Pulse ox is not a good monitor or
Ventilation
Anemia
Bronchial intubation
The pulse oximeter is a noninvasive monitor of
Hemoglobin saturation
Heart rate
Fluid responsiveness
Useful to asses perfusion?
Pulse oximeter
May be compressed during mediatinoscopy
The brachiocephalic (innominate) artery
Innominate artery supplies blood to
right arm, head and neck
First branch of the aortic arch?
Innominate artery
Third branch off the AORTA
Innominate
What are the 2 branches off the aorta
Left and right coronary arteries.
Where do you place pulse ox probe to monitor foot perfusion in the lithotomy position?
Placement on the toe
Pulse ox can monitor for shoulder arthroscopy?
Brachial artery compression during shoulder arthroscopy
Does the pulse oximeter monitor anemia?
NO
SPO2 monitors the
% of hemoglobin bound with oxygen
If the Hgb is fully saturate with oxygen, then the
SPO2 will continue to read 100%
2 parameters highly depended on the amount of Hgb
Oxygen carrying capacity (CaO2) Oxygen delivery (DO2)
May overestimated SPO2 with
Severe anemia.
Does the pulse oximeter monitor VENTILAITON
NO
Alveolar oxygen equation
Alveolar oxygen = FiO2 x (Pb - PH2O) - PaCO2/RQ
Just because a patient does not desaturate does not mean
The Endotracheal tube is not positioned in the left or right bronchus.
Assessment of bronchial intubation is better accomplished by
Presencee of bilateral breath sounds
Chest X-ray
Visualizing the CARINA through a fiberoptic bronchoscope.
Bronchial intubation and PIP
ACUTE rise in PIP during volume controlled ventilation may signal a bronchial intubation . As you withdraw the ETT, the peak inspiratory pressure and the pressure and flow volume should return to baseline.
How does the LVAD affect pulse ox reading?
Unlike a healthy heart that delivers pulsatile flow to the body, the LVAD supplements the failing myocardium with non-pulsatile flow.
How does the carboxyhemoglobin affect Pulse ox reading
Carboxyhemoglobin absorbs the same wavelength as oxyhemoglobin. This causes the pulse ox to overestimate the degree of oxygen bound to hemoglobin.
Nail polish and pulse ox reading
False reduction in SPO2
Pulse ox has a margin of error
2-3 percent when the SPO2 is between 70–100%
Margin of error for pulse ox 50-70%
3%
Dysfunctional oxygen species include
Methemoglobin
Carboxyhemoglobin
Methemoglobin absorbs
660nm ; 940 nm equally
Methemoglobin absorption
the 1:1 absorption ratio is read as 85%
Methomoglobin falsely underestimated SPO2 if O2 sat
> 85 %
Methomoglobin falsely overestimated SPO2 if O2 sat
< 85%
Carboxyhemoglobin absorbs
660nm to the same degree as O2-Hgb
Decreased perfusion affecting SPO2
vasoconstriction
Hypothermia
Hypoperfusion
Raynaud’s syndrome
Altered optical characteristics affecting pulse ox
Dyes such as methylene blue,
Indocyanine green, and INDIGO CARMINE
Nail polish colors affecting pulse ox
Black
Blue
Green
Non-pulsatilve flow affecting pulse ox
CPB
LVAD
Motion artifact that affects pulse ox
shivering
movement and positioning of patient.
Factors that DO NOT AFFECT reliabiity of pulse ox
Jaundice
Hgb F and S
Polycythemia
Acrylic finger nails.
What is the most common method of measuring exhaled gases inside the breathing circuit?
infrared absorption (each gas as signature fingerprint)
The greater the partial pressure of a gas inside the breathing circuit,
The greater the partial pressure of that gas delivered to the gas analyzer.
Infrared absorption spectrophotometry determines
Concentration and identities of all sample gases simultaneously
Does OXYGEN absorbed infrared light?
No
Concentration of OXYGEN MUST BE MEASURE BY WHAT MEANS?
- GALVANIC CELL or clark electrode
2. PARAMAGNETIC ANALYSIS
What is mass spectometry?
Bombards a gas samples with electrons creating ion fragments
New tool that can detect, inspired, expired and breath to breath changes of a particular gas by incorporating a lipid layer on the crystal?
Piezoelectric crystals.
Which phase of the CO2 waveform BEST corresponds to the ventilation-perfursion status?
Plateau phase (phase III)
CO2 follows a concentration gradient as it exits the body
Blood > lungs> Airway > Sample line or atmosphere.
Infraed anaylysis is the most common method of measuring
CO2,
N2O
Halogenated anesthetics.
Molecules that contain 2 or more dissimilar atoms do what?
absorb Infrared light
Why can’t infrared analysis measure oxygen, helium, nitrogen or xenon
Becauses these species only contain ONE TYPE OF ATOM
Sampling methods with less apparatus dead space
Sidestream.
Response time with sidestream is
Slower
Red light 660nm is preferentially absorbed by
Reduced Hgb
Near infrared light (990nm) is preferentially absorbed by
HgbO2
SPO2 and mmHG
40, 50, 60
70, 80,90 respectively
Determinants of dynamic compliance are
PEEP
PIP
TV
No changes in dynamic or status compliance with this?
PE
This causes decreased dynamic compliance
Mucus plus
This causes Decrease static compliance
Endobronchial intubation