Aortic and Branchial derivatives Flashcards
derivative of the 1st aortic arch
part of the maxiallary artery (branch of the external carotid)
derivate of the 2nd aortic arch
stapedial artery
hyoid artery
derivative of the 3rd aortic arch
common carotid
proximal of the internal carotid
deritave of the 4th aortic arch on the right
proximal part of the subclavian artery where the right recurrent laryngeal wraps around
derivative of the 4th aortic arch on the left
aortic arch
derivative of the 5th aortic arch
nothing jk
derivative of the 6th aortic arch on the left
ductus arterois
proximal part of the pulmonary artery
where left recurrent laryngeal nerce gets caught
derivative of the 6th aortic arch on the right
proximal part of the pulmonary artery
where is the right recurrent laryngeal nerve?
on the derivative of the 4th aortic arch - proximal part of the subclavian
where is the left recurrent laryngeal nerve?
on the derivative of the 6th aortic arch - ductus arteriosus
what are the branchial clefts made of
ectoderm
what are the branchail arches made of
mesoderm - muscle and artery
neural crest cells - bone and cartilage
what are the branchial pouches made of
endoderm
what does the 1st branchail cleft become
external auditory meatus
external auditory meatus
1st branchial cleft - ectoderm
what does the 2nd through 4th clefts become
temporary cervial sinuses - obliterate by proliferation of second arch mesenchyme
what is a branchial cleft cyst
in lateral neck
persistence of the cerivical sinus formed from the 2nd thorugh 4th branchial clefts
cartilage from the first branchial arch please
meckels cartilage: mandible, malleus, incus, sphenomandibular ligament
muscles from the first branchial arch please
muscles of mastication: temporalis, masseters, lateral pterygoind, medial pterygoid, anterior bello fo digastric, tensor tympani, tensor veli palatini
what nerves associated with the first branchial arch
V2 and V3
what is treacher collins syndrome
first branchial arch neural crest cells fail to migrate = mandibular hypoplasia and facial abnormalities (lmandbile, malleus, incus, spenomandibular ligamnet)
what cartilage from the second arch
reichert cartilage - stapes, styloid process, lesser horn of hyoid and stylohyoid ligmanet
muscles from second arch
muscles of facial expression, stapedius, stylohoid ,platysma, posterior belly of digastric
nerve associated with second branchial arch
VII
what is congenital pharyngocutaneous fistula
persistence of second cleft and pouch - fistula between tonsillar area and lateral neck
fistula between tonsillar area and lateral neck
persistence of second cleft and pouch - a congenital pharyngocutaneous fistula
what cartilage from the third branchail arch
greater horn of the hyoid
what muscle from the third branchial arch
stylopharyngeus
what nerve for third branchial arch
IX
what cartilage from the fourth to sixth branchial arches
thyroid, cricoid, arytenoids, corniculate, cuneiform
what muscles with the fourth arch
most pahyrngeal constrictors, cricothyroid, levator veli palatini
what nerve with fourth arch
superior laryngeal branch X
what muscle with sixth arch
all intrinsic muscles fo larynx except cricothyroid
what nerve with sixth arch
recureent laryngeal branch of CN X
what arches make up tongue
third and fourth make up posterior 1/3 of tongue
what comes from the fifth arch
nothing
what CN are both motor and sensory
the ones associated with the branchial arches
V3 (not V2), VII, IX and X
what comes from the first branchial pouch
middle ear cavity, eustachain tube, mastoid air cells
describe where the ear comes from
external auditory meatus = first branchial cleft
malleusand incus - from first branchial arch
stapedius = second branchial arch
middle ear cavity, eustachian tube, mastoid air cells = first branchail pouch
what comes from the second branchial pouch
epithelial lining of the palatine tonsil
which pouch contributes to endoderm lined structures fo ear
first branchial pouch
what comes from teh dorsal wings of the third branchial pouch
inferior parathyroids
what comes from teh ventral wings of the third pouch
the thymus
what comes from the third pouch
2x inferior thyroids
1x thymus
what comes from the fourth pouch
dorsal wing - superior parathyroids
list everything that comes from the fisrt branchial cleft/arch/pouch
first cleft - external auditory meatus
first arch - mandible, malleus, incus, sphenomandibular ligament AND muscles of mastication, mylohyoid, anterior belly of digastric, tensor veli palatini, tensor tympani AND CN V2 and V3
first pouch: middle ear cavity, eustachian tube, mastoid air cells
list everythign that comes from the second branchial cleft/arch/pouch
second cleft - cervical sinus
second arch - stapes, styloid process, lesser horn of hyoid, stylohyoid AND muscles fo facial expression, stapeduis, stylohyoind , platysma, posterior belly of digastric, Cn VII
second pouch - epithelial lining of palatine tonsil
list everythign that comes from third branchial cleft/arch/pouch
third cleft - cervical sinus
third arch - greater horn of hyoid AND stylopharyngeous, IX
third pouch - inferior parathyroids, thymus
list everything that comes from the fourth branchial cleft/arch/pouch
fourth cleft - cervical sinus
fourth arch - thyorid cricoid aryteniods coniculate and cuneiform cartilages AND most pharyngeal constrictors and cirticothyroid and levator veli palatini with CN X superior laryngeal
foruth pouch - superior parathyroids
list everythign that comes from fifth branchial cleft/arch/pouch
nothing
list everything that comes from the sixth branchial cleft/arch/pouch
cleft - nothing
arch - thyroid, cricoid, arytenoids, corniculate and cuneiform cartilages AND all intrinsic muscles fo layrnx excetp ricothyroid AND CN X recurrent laryngeal nerve
describe the pathogenesis of DiGeorge
failure of the third adn foruth branchial pouches
describe de george syndrome
thymic aplasia (no third pouch) = T cell deficiency parathyroid agenesis (no third or fourth pouch) = hypocalcemia cardiac defects (conotronucal amonalies)
what is MEN2a pathogenesis
RET oncogence mutatlion
failure of neural crest cells
describe Men 2A
pheochromocytoma @ adrenal cortex
parathryoid tumor - 3rd and 4th parhngeal pouch
medullary thyroid cancer/parafollicular cells - from neural crest cells and associated wiht 4th and 5th pahryngeal pouches.
