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PODT > Anxiolytics > Flashcards

Anxiolytics Flashcards

1
Q

Mechanism of benzodiazepines

A

Act on GABA-A receptor to increase frequency of chloride channel opening

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2
Q

Side effects of benzodiazepines

A

Confusion, headache, amnesia
Ataxia
Disinhibition
Blurred vision/dysarthria

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3
Q

What drug is used for alcohol withdrawal syndrome

A

Diazepam

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4
Q

What is benzodiazepine overdose treated with

A

Flumazenil - antagonises benzodiazepines binding site

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5
Q

What 2 benzodiazepines can lead to addiction

A

Lorazepam

Alprazolam

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6
Q

Mechanism and use of Z drugs (zolpidem, zopiclone)

A

Bind to alpha 1 chloride channel on gaba-A

Hypnotic

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7
Q

Barbituates mechanism

A

Increase duration of GABA receptor

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8
Q

Mechanism of pregabalin

A

DecreSes excitatory neurotransmission on gated calcium channels

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9
Q

Mechanism of buspirone

A

Agonist at presynaptic 5HT1A receptors to decrease negative feedback and increase serotonin release and partial agonist at post synaptic 5HT1A to decrease serotonin neurotransmission
Presynaptic D2/3 antagonist

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PODT (13 decks)

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