Anti-pyschotics Flashcards

1
Q

Extra pyramidal side effects of 1st gen antipsychotics

A
Acute dystonia 
Parkinsonism 
Akathisia
Tardive dyskinesia
Hyperprolactinaemia
Neuroleptic malignant syndrome
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2
Q

How to solve tardive dyskinesia

A

Stop anti cholinergics as it’s due to upregulation of D2 receptors
Swap to 2nd gen
Decrease antipsychotic dose

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3
Q

How to solve akathisia

A

propranolol

5HT2 antagonist- mirfazapine

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4
Q

What is neuroleptic malignant syndrome

A

Fever confusion muscle rigidity
Autonomic disturbance
Rhabdomyolysis—> renal failure

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5
Q

What are the 2nd gen antipsychotics that cause weight gain, dyslipidaemia and type II diabetes

A

Clozapine
Quetapine
Olanzapine
Risperidone?

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6
Q

WhAt antipsychotics cause QT prolongation

A

Quetapine

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7
Q

WhAt receptor is sedation, dry mouth/constipation, postural hypotension caused by

A

Histamine
Muscarinic
Adrenergic

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8
Q

Side effects of clozapine

A

Neutropenia

Myocarditis

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9
Q

What can aripiprazole cause

A

Akathisia

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