Anti-pyschotics Flashcards
Extra pyramidal side effects of 1st gen antipsychotics
Acute dystonia Parkinsonism Akathisia Tardive dyskinesia Hyperprolactinaemia Neuroleptic malignant syndrome
How to solve tardive dyskinesia
Stop anti cholinergics as it’s due to upregulation of D2 receptors
Swap to 2nd gen
Decrease antipsychotic dose
How to solve akathisia
propranolol
5HT2 antagonist- mirfazapine
What is neuroleptic malignant syndrome
Fever confusion muscle rigidity
Autonomic disturbance
Rhabdomyolysis—> renal failure
What are the 2nd gen antipsychotics that cause weight gain, dyslipidaemia and type II diabetes
Clozapine
Quetapine
Olanzapine
Risperidone?
WhAt antipsychotics cause QT prolongation
Quetapine
WhAt receptor is sedation, dry mouth/constipation, postural hypotension caused by
Histamine
Muscarinic
Adrenergic
Side effects of clozapine
Neutropenia
Myocarditis
What can aripiprazole cause
Akathisia