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PHRM 845 > Anxiety Ott > Flashcards

Anxiety Ott Flashcards

1
Q

drugs that can cause anxiety

A

albuterol
caffeine
decongestants
levothyroxine
stimulants
steroids

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2
Q

buspirone is approved for what disorder

A

generalized anxiety disorder

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3
Q

buspirone target dose

A

10-15 mg TID

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4
Q

how long for buspirone efficacy

A

3-4 weeks for initial

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5
Q

why are benzos not really recomended as first line?

A

abuse potential
not good to be on long term

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6
Q

acute withdrawal of benzos can lead to what?

A

life-threatening seizures

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7
Q

warnings with benzos

A

other CNS depressants, opioids

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8
Q

benzos with no active metabolite

A

alprazolam
lorazepam
clonazepam
oxazepam

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9
Q

benzos with long acting metabolite

A

diazepam
clorazepate
chlordiazepoxide

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10
Q

side effects of benzos

A

sedation
paradoxical excitement
swallowing difficulties
memory impairment
psychomotor impairment

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11
Q

benzo taper off lasts

A

weeks to months

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12
Q

can we give benzos in elderly

A

Beers, >65 is a risk

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13
Q

elderly preferred benzos

A

lorazepam, oxazepam, temazepam

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14
Q

hydroxyzine is fda approved for what

A

generalized anxiety disorder

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15
Q

hydroxyzine is the most commonly used what

A

as needed drug for anxiety or insomnia instead of a benzo

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16
Q

risk with hydroxyzine

A

QTC

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17
Q

side effects with hydroxyzine

A

sedation and anticholinergic

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18
Q

hydroxyzine in elderly?

A

avoid

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19
Q

propranolol useful for

A

performance and situational anxiety

20
Q

doses of propranolol that are effective

A

low doses

21
Q

what history to watch out for with propranolol

A

asthma, cardiovascular

22
Q

natiral products for anxiety

A

Kava, St Johns Wort, passionflower, valerian, chamomile

23
Q

when could we consider gabapentenoids

A

pt with bipolar and anxiety/neuropathic pain

24
Q

qutiapine in sleep?

A

no

25
Q

first line therapy for all anxiety disorders

A

SSRis, SNRis
buspirone for generalized too

26
Q

atypical antipsychotics could be used for what

A

OCD (treatment resistant)

27
Q

atypical antipsychotics we could use for OCD / anxiety

A

aripiprazole, risperidone

28
Q

gerneralized anxiety disorder diagnosis

A

excessive anxiety / worry for at least 6 months
three symptoms:
restlessness
easily fatigued
concentration
irritable
muscle tension
sleep disturb

29
Q

SNRIs especially useful if what

A

patient has a pain syndrome

30
Q

benzodiazepine use in GAD

A

bridge therapy
cover time till SSRi/SNRi onset

31
Q

what is social anxiety

A

fear about social, performance situations in which pt fears embarrassment/humiliation

32
Q

social anxiety disorder treatment

A

SSRI
beta blocker (non generalized performacnce social anxiety)

33
Q

panic disorder criteria

A

recurrent panic attacks
4 sx: sweating, palpitations, nausea, dixxy, fear of losing control, going crazy
at least one followed by concerns or changes

34
Q

panic disorder treatment

A

SSRis
SNRIs - venlafaxine
benzos - last line

35
Q

obsessions

A

intrusive thoughts causing anxiewty

36
Q

complusions

A

repetitive behaviors

37
Q

OCD treatment

A

SSRis
second line: clomipramine

38
Q

symptom reduction with OCD

A

25-50%

39
Q

OCD augmentation therapy with antipsychotics

A

risperidone, aripiprazoleq

40
Q

cardinal signs of PTSD

A

flashbacks
reexperience
avoidance
hypervigilance

41
Q

treatment of PTSD

A

SSRI/SNRi

42
Q

drug helpful for nightmares in PTSD

A

prazosin

43
Q

which drug class should not be used with PTSD

A

benzos

44
Q

jitteriness can occur with what drug classes

A

SSRI,SNRI
start with lower doses

45
Q

non drug treatments are especially helpful in PTSD with waht

A

events occuring over a long period of time

PHRM 845 (32 decks)

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