Anxiety

Question 1

Background information for Benzodiazepines

Answer 1

There are two benzodiazepine receptor subtypes, BNZ1 and BNZ2. BNZ1 receptor activation promotes sleep. BNZ2 receptor activation promotes muscle relaxation

Question 2

Pharmacology of Benzodiazepines

Answer 2

Benzodiazepines bind to benzodiazepine receptors and enhance the effect of gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter of the central nervous system. These effects can be useful in the treatment of anxiety, insomnia, muscle spasms, seizures, and other conditions

Question 3

Indications of Benzodiazepines

Answer 3

• Anxiety
• Insomnia
• Agitation
• Seizures
• Muscle spasms
• Alcohol withdrawal

Question 4

Side effects of Benzodiazepines

Answer 4

• Drowsiness
• Somnolence (strong desire to fall asleep)
• Dependency

Question 5

Drug interactions of Benzodiazepines

Answer 5

• Increased drowsiness when used with other drugs that suppress the central nervous system

Question 6

List the brand names and generic names

Answer 6

Brand Name: Xanax (C-IV), Librium (C-IV), Onfi (C-IV), Klonopin (C-IV), Valium [Diastat] (C-IV), Ativan (C-IV), Versed (C-IV), Restoril (C-IV), Halcion (C-IV)

Generic Name: Alprazolam (C-IV), Chlordiazepoxide (C-IV), Clobazam (C-IV), Clonazepam (C-IV), Diazepam (C-IV), Lorazepam (C-IV), Midazolam (C-IV), Temazepam (C-IV), Triazolam (C-IV)

Question 7

What do Benzodiazepines end with?

Answer 7

“-azepam” “-azolam”

Question 8

What is the antidote for Benzodiazepines

Answer 8

Romazicon (flumazenil)