Antivirals Flashcards
Brand name
Acyclovir
Zovirax
Brand name
Atazanavir
Reyataz
Brand name
Elbasivir/Grazoprevir
Zepatier
Brand name
Efavirenz
Sustiva
Brand name
Emtricitabine/Tenofovir
Truvada
Brand name
Entecavir
Baraclude
Brand name
Glecaprevir/Pinremtasvir
Mavyret
Brand name
Maraviroc
Selzentry
Brand name
Oseltamivir
Tamiflu
Brand name
Raltegravir
Insentress
Brand name
Sofosbuvir
Sovaldi
Brand name
Valacyclovir
Valtrex
This drug is a neuraminidase inhibitor and indicated for treatment and Prophy as well as children older than 1 yo and adults
a.acyclovir
b.valtrex
c.tamiflu
d.selzentry
tamiflu
This considered to be a viral DNA polymerase inhibitor and is indicated for
herpes simplex(genital,cold sores),herpes zoster(shingles),varicella(chicken pox)
a.efanvirenz
b.zovirax
c.entecavir
d.insentress
zovirax
This is a NS3/A4 protease inihibitor and is indicated for chronic HCV(genotype 1/4 ) also +/- for ribavin
b.sofosbuvir
c.maraviroc
d.atazanavir
a.elbasivir/grazoprevir
elbasivir/grazoprevir
A polymerase inihibitor that is indicated for chronic HCV genotype 1-4, combo with ribavirin/peginterferon, velpatsavir,velpatsavir, voxilaprevir and ledipasvir
a.valtrex
b.zovirax
c.baraclude
d.sovaldi
sovaldi
This is a reverse transcriptase inhibitor and is indicated for HBV
a.entecavir
b.atazanavir
c.oseltamivir
d.maraviroc
entecavir
This drug is an nucleoside reverse transcriptase inhibitor, alone it is used for preexposure prophy, however in a combo with other retrovirals it is used to treat HIVTx
a.tamiflu
b.truvada
c.sustiva
d.mavyret
truvada
This drug is a non-nucleotide transcriptase inhibitor and when used with other retrovirals treats HIV
a.Zepatier
b.Sustiva
c.Valtrex
d.Zovirax
Sustiva
All of the following is used to treat HIV except:
a.Emtricitabine/Tenofovir
bAtazanavir
c.Raltegravir
d.Sofosbuvir
e.Marav
sofosbuvir
This ccr5 antagonist acts by slectively and reversibly binds to the chemokine motif receptor 5 corecptors located on human CD4 cells
a.selzentry
b.isentress
c.mavyret
d.reyataz
selzentry
Which of the following acts by inhibiting the catalytic activity of HIV-1 integrase, preventing the integration of viral DNA into host strand
a.glecaprevir/pinremtasvir
b.valtrex
c.sovaldi
d.insentress
isentress
Binding to HIV-1 protease activity thus inhibitng the cleavage of Gag-pol polyprotein precursors into functional proteins necessary for mature virions
a.sustiva
b.selzentry
c.reyataz
d.acyclovir
reyataz
This binds to HIV reverse transcirptase,blocking DNA polymerase activities
a.valtrex
b.efavirenz
c.zepatier
d.truvada
efavirenz
Each drug in this combo therapy interferes with HIV viral RNA-dependent DNA polymerase
a.Sovaldi
b.Mavyret
c.Truvada
d.Zepatier
Truvada
This drug acts by inhibiting HBV polymerase base priming, reverse transcription of the negative strand fron the pregenomic messenger RNA, and synthesis of positive-strand HBV DNA
a.Baraclude
b.Maraviroc
c.Raltegravir
d.Tamiflu
Baraclude
This drug acts by inhibiting HCV NS5B RNA-dependent RNA polymerase
a.oseltmavir
b.maraviroc
c.Sofosbuvir
d.zovirax
sofosbuvir
This drug acts by inhibitng HCV NS5B RNA-dependent RNA polymerase AND inhibits NS58/4 protease which cleaves the HCV polyprotein into mature forms
a. elbasivir/grazoprevir
b.entecavir
c.valacyclovir
d.raltegravir
elbasivir/grazoprevir
This is an acyclic nucleoside analogue that competitively inhibits viral DNA synthesis
a. zepatier
b.reyataz
c.zorivax
d.sustiva
zovirax
This is an inhibitor of influenza virus neuraminidase which prevents viral progeny from detaching from cell envelope
a.selzentry
b.oseltamivir
c.valtrex
d.zovirax
oseltamivir
A major contrainidcation of this drug is that it interferes with influenza vaccine effectiveness
a.tamiflu
b.zovirax
c.baraclude
d.sovaldi
tamiflu
When on this antiviral there is a possible DI with foscarnet,varicella and zoster vaccine, therfore caution must be taken.Which of the following drugs is this?
a.elbasivir/grazoprevir
b.emtricitabine/tenofovir
c.acyclovir
d.reyataz
acyclovir
BBW for these two drugs is HBV reactivation
a.elbasivir/grazoprevir
b.truvada
c.sustiva
d.baraclude
e.sovaldi
- elbasivir/grazoprevir
- sovaldi
Use in pregancy and with amiodarone as well as p-glycoprotein inhibitors/inducers are major contraindicatios for this drug
a.valtrex
b.sofosbuvir
c.mavyret
d.tamiflu
sofosbuvir
This drug has a BBW of HBV resistance in HIV coinfected, disease exacerbation upon d/c, lactic acidosis
a.insentress
b.sustiva
c.entecavir
d.zepatier
entecavir
Ribavirin and ganciclovir are contraindicated in patients on this treatment
a.efavirenz
b.glecaprevir/pinremtasvir
c.acyclovir
d.baraclude
baraclude
BBW for this antiviral include HBV exacerbation,lactic acidosis, drug resistance with PrEP
a.voltrex
b.truvada
c.zovirax
d.insentress
truvada
CI: Hypersensitivity, bepridil, cisapride, elbasvir,
grazoprevir, midazolam, pimozide, triazolam, St. John’s
wort, or ergot alkaloids
* DI: various CYP enzymes, oral contraceptives, QTc
prolonging agents
Which of the following drugs does this reference
a.entecavir
b.Efavirenz
c.maraviroc
d.raltegravir
efavirenz
Antacid (separate dosing), Cyp 3a4, PR or QTc
prolongers, oral contraceptives, PPI and H2 blockers,
UGT1A1 sybstrates are contratindications listed for which drugs?
a.Reyatza
b.acyclovir
c.entacavir
d.oseltamivir
reyatza
DI: antacids (separate dosing), fosamprenavir, rifampin,
PPI and H2 blockers
a. Zovirax
b.selzentry
c.atazanavir
d.insentress
insentress
CI: CrCl less than 30 mL/min or ESRD who are taking potent CYP3A4/5 inhibitors or inducers
* DI: Cyp3A4 inhibitors or inducers
a.maraviroc
b.valtrex
c.sustiva
d.zepatier
maraviroc
