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Top 300 Medications > Antivirals > Flashcards

Antivirals Flashcards

1
Q

Brand name

Acyclovir

A

Zovirax

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2
Q

Brand name

Atazanavir

A

Reyataz

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3
Q

Brand name

Elbasivir/Grazoprevir

A

Zepatier

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4
Q

Brand name

Efavirenz

A

Sustiva

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5
Q

Brand name

Emtricitabine/Tenofovir

A

Truvada

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6
Q

Brand name

Entecavir

A

Baraclude

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7
Q

Brand name

Glecaprevir/Pinremtasvir

A

Mavyret

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8
Q

Brand name

Maraviroc

A

Selzentry

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9
Q

Brand name

Oseltamivir

A

Tamiflu

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10
Q

Brand name

Raltegravir

A

Insentress

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11
Q

Brand name

Sofosbuvir

A

Sovaldi

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12
Q

Brand name

Valacyclovir

A

Valtrex

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13
Q

This drug is a neuraminidase inhibitor and indicated for treatment and Prophy as well as children older than 1 yo and adults

a.acyclovir
b.valtrex
c.tamiflu
d.selzentry

A

tamiflu

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14
Q

This considered to be a viral DNA polymerase inhibitor and is indicated for
herpes simplex(genital,cold sores),herpes zoster(shingles),varicella(chicken pox)

a.efanvirenz
b.zovirax
c.entecavir
d.insentress

A

zovirax

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15
Q

This is a NS3/A4 protease inihibitor and is indicated for chronic HCV(genotype 1/4 ) also +/- for ribavin

b.sofosbuvir
c.maraviroc
d.atazanavir

a.elbasivir/grazoprevir

A

elbasivir/grazoprevir

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16
Q

A polymerase inihibitor that is indicated for chronic HCV genotype 1-4, combo with ribavirin/peginterferon, velpatsavir,velpatsavir, voxilaprevir and ledipasvir

a.valtrex
b.zovirax
c.baraclude
d.sovaldi

A

sovaldi

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17
Q

This is a reverse transcriptase inhibitor and is indicated for HBV

a.entecavir
b.atazanavir
c.oseltamivir
d.maraviroc

A

entecavir

18
Q

This drug is an nucleoside reverse transcriptase inhibitor, alone it is used for preexposure prophy, however in a combo with other retrovirals it is used to treat HIVTx

a.tamiflu
b.truvada
c.sustiva
d.mavyret

A

truvada

19
Q

This drug is a non-nucleotide transcriptase inhibitor and when used with other retrovirals treats HIV

a.Zepatier
b.Sustiva
c.Valtrex
d.Zovirax

A

Sustiva

20
Q

All of the following is used to treat HIV except:

a.Emtricitabine/Tenofovir
bAtazanavir
c.Raltegravir
d.Sofosbuvir
e.Marav

A

sofosbuvir

21
Q

This ccr5 antagonist acts by slectively and reversibly binds to the chemokine motif receptor 5 corecptors located on human CD4 cells

a.selzentry
b.isentress
c.mavyret
d.reyataz

A

selzentry

22
Q

Which of the following acts by inhibiting the catalytic activity of HIV-1 integrase, preventing the integration of viral DNA into host strand

a.glecaprevir/pinremtasvir
b.valtrex
c.sovaldi
d.insentress

A

isentress

23
Q

Binding to HIV-1 protease activity thus inhibitng the cleavage of Gag-pol polyprotein precursors into functional proteins necessary for mature virions

a.sustiva
b.selzentry
c.reyataz
d.acyclovir

A

reyataz

24
Q

This binds to HIV reverse transcirptase,blocking DNA polymerase activities

a.valtrex
b.efavirenz
c.zepatier
d.truvada

A

efavirenz

25
Q

Each drug in this combo therapy interferes with HIV viral RNA-dependent DNA polymerase

a.Sovaldi
b.Mavyret
c.Truvada
d.Zepatier

A

Truvada

26
Q

This drug acts by inhibiting HBV polymerase base priming, reverse transcription of the negative strand fron the pregenomic messenger RNA, and synthesis of positive-strand HBV DNA

a.Baraclude
b.Maraviroc
c.Raltegravir
d.Tamiflu

A

Baraclude

27
Q

This drug acts by inhibiting HCV NS5B RNA-dependent RNA polymerase

a.oseltmavir
b.maraviroc
c.Sofosbuvir
d.zovirax

A

sofosbuvir

28
Q

This drug acts by inhibitng HCV NS5B RNA-dependent RNA polymerase AND inhibits NS58/4 protease which cleaves the HCV polyprotein into mature forms

a. elbasivir/grazoprevir
b.entecavir
c.valacyclovir
d.raltegravir

A

elbasivir/grazoprevir

29
Q

This is an acyclic nucleoside analogue that competitively inhibits viral DNA synthesis

a. zepatier
b.reyataz
c.zorivax
d.sustiva

A

zovirax

30
Q

This is an inhibitor of influenza virus neuraminidase which prevents viral progeny from detaching from cell envelope
a.selzentry
b.oseltamivir
c.valtrex
d.zovirax

A

oseltamivir

31
Q

A major contrainidcation of this drug is that it interferes with influenza vaccine effectiveness

a.tamiflu
b.zovirax
c.baraclude
d.sovaldi

A

tamiflu

32
Q

When on this antiviral there is a possible DI with foscarnet,varicella and zoster vaccine, therfore caution must be taken.Which of the following drugs is this?
a.elbasivir/grazoprevir
b.emtricitabine/tenofovir
c.acyclovir
d.reyataz

A

acyclovir

33
Q

BBW for these two drugs is HBV reactivation
a.elbasivir/grazoprevir
b.truvada
c.sustiva
d.baraclude
e.sovaldi

A
  • elbasivir/grazoprevir
  • sovaldi
34
Q

Use in pregancy and with amiodarone as well as p-glycoprotein inhibitors/inducers are major contraindicatios for this drug
a.valtrex
b.sofosbuvir
c.mavyret
d.tamiflu

A

sofosbuvir

35
Q

This drug has a BBW of HBV resistance in HIV coinfected, disease exacerbation upon d/c, lactic acidosis
a.insentress
b.sustiva
c.entecavir
d.zepatier

A

entecavir

36
Q

Ribavirin and ganciclovir are contraindicated in patients on this treatment
a.efavirenz
b.glecaprevir/pinremtasvir
c.acyclovir
d.baraclude

A

baraclude

37
Q

BBW for this antiviral include HBV exacerbation,lactic acidosis, drug resistance with PrEP
a.voltrex
b.truvada
c.zovirax
d.insentress

A

truvada

38
Q

CI: Hypersensitivity, bepridil, cisapride, elbasvir,
grazoprevir, midazolam, pimozide, triazolam, St. John’s
wort, or ergot alkaloids
* DI: various CYP enzymes, oral contraceptives, QTc
prolonging agents
Which of the following drugs does this reference
a.entecavir
b.Efavirenz
c.maraviroc
d.raltegravir

A

efavirenz

39
Q

Antacid (separate dosing), Cyp 3a4, PR or QTc
prolongers, oral contraceptives, PPI and H2 blockers,
UGT1A1 sybstrates are contratindications listed for which drugs?
a.Reyatza
b.acyclovir
c.entacavir
d.oseltamivir

A

reyatza

40
Q

DI: antacids (separate dosing), fosamprenavir, rifampin,
PPI and H2 blockers
a. Zovirax
b.selzentry
c.atazanavir
d.insentress

A

insentress

41
Q

CI: CrCl less than 30 mL/min or ESRD who are taking potent CYP3A4/5 inhibitors or inducers
* DI: Cyp3A4 inhibitors or inducers
a.maraviroc
b.valtrex
c.sustiva
d.zepatier

A

maraviroc

42
Q
A

Top 300 Medications (16 decks)

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