Antivirals

Question 1

Brand name

Acyclovir

Answer 1

Zovirax

Question 2

Brand name

Atazanavir

Answer 2

Reyataz

Question 3

Brand name

Elbasivir/Grazoprevir

Answer 3

Zepatier

Question 4

Brand name

Efavirenz

Answer 4

Sustiva

Question 5

Brand name

Emtricitabine/Tenofovir

Answer 5

Truvada

Question 6

Brand name

Entecavir

Answer 6

Baraclude

Question 7

Brand name

Glecaprevir/Pinremtasvir

Answer 7

Mavyret

Question 8

Brand name

Maraviroc

Answer 8

Selzentry

Question 9

Brand name

Oseltamivir

Answer 9

Tamiflu

Question 10

Brand name

Raltegravir

Answer 10

Insentress

Question 11

Brand name

Sofosbuvir

Answer 11

Sovaldi

Question 12

Brand name

Valacyclovir

Answer 12

Valtrex

Question 13

This drug is a neuraminidase inhibitor and indicated for treatment and Prophy as well as children older than 1 yo and adults

a.acyclovir
b.valtrex
c.tamiflu
d.selzentry

Answer 13

tamiflu

Question 14

This considered to be a viral DNA polymerase inhibitor and is indicated for
herpes simplex(genital,cold sores),herpes zoster(shingles),varicella(chicken pox)

a.efanvirenz
b.zovirax
c.entecavir
d.insentress

Answer 14

zovirax

Question 15

This is a NS3/A4 protease inihibitor and is indicated for chronic HCV(genotype 1/4 ) also +/- for ribavin

b.sofosbuvir
c.maraviroc
d.atazanavir

a.elbasivir/grazoprevir

Answer 15

elbasivir/grazoprevir

Question 16

A polymerase inihibitor that is indicated for chronic HCV genotype 1-4, combo with ribavirin/peginterferon, velpatsavir,velpatsavir, voxilaprevir and ledipasvir

a.valtrex
b.zovirax
c.baraclude
d.sovaldi

Answer 16

sovaldi

Question 17

This is a reverse transcriptase inhibitor and is indicated for HBV

a.entecavir
b.atazanavir
c.oseltamivir
d.maraviroc

Answer 17

entecavir

Question 18

This drug is an nucleoside reverse transcriptase inhibitor, alone it is used for preexposure prophy, however in a combo with other retrovirals it is used to treat HIVTx

a.tamiflu
b.truvada
c.sustiva
d.mavyret

Answer 18

truvada

Question 19

This drug is a non-nucleotide transcriptase inhibitor and when used with other retrovirals treats HIV

a.Zepatier
b.Sustiva
c.Valtrex
d.Zovirax

Answer 19

Sustiva

Question 20

All of the following is used to treat HIV except:

a.Emtricitabine/Tenofovir
bAtazanavir
c.Raltegravir
d.Sofosbuvir
e.Marav

Answer 20

sofosbuvir

Question 21

This ccr5 antagonist acts by slectively and reversibly binds to the chemokine motif receptor 5 corecptors located on human CD4 cells

a.selzentry
b.isentress
c.mavyret
d.reyataz

Answer 21

selzentry

Question 22

Which of the following acts by inhibiting the catalytic activity of HIV-1 integrase, preventing the integration of viral DNA into host strand

a.glecaprevir/pinremtasvir
b.valtrex
c.sovaldi
d.insentress

Answer 22

isentress

Question 23

Binding to HIV-1 protease activity thus inhibitng the cleavage of Gag-pol polyprotein precursors into functional proteins necessary for mature virions

a.sustiva
b.selzentry
c.reyataz
d.acyclovir

Answer 23

reyataz

Question 24

This binds to HIV reverse transcirptase,blocking DNA polymerase activities

a.valtrex
b.efavirenz
c.zepatier
d.truvada

Answer 24

efavirenz

Question 25

Each drug in this combo therapy interferes with HIV viral RNA-dependent DNA polymerase | a.Sovaldi b.Mavyret c.Truvada d.Zepatier

Answer 25

Truvada

Question 26

This drug acts by inhibiting HBV polymerase base priming, reverse transcription of the negative strand fron the pregenomic messenger RNA, and synthesis of positive-strand HBV DNA | a.Baraclude b.Maraviroc c.Raltegravir d.Tamiflu

Answer 26

Baraclude

Question 27

This drug acts by inhibiting HCV NS5B RNA-dependent RNA polymerase | a.oseltmavir b.maraviroc c.Sofosbuvir d.zovirax

Answer 27

sofosbuvir

Question 28

This drug acts by inhibitng HCV NS5B RNA-dependent RNA polymerase AND inhibits NS58/4 protease which cleaves the HCV polyprotein into mature forms | a. elbasivir/grazoprevir b.entecavir c.valacyclovir d.raltegravir

Answer 28

elbasivir/grazoprevir

Question 29

This is an acyclic nucleoside analogue that competitively inhibits viral DNA synthesis | a. zepatier b.reyataz c.zorivax d.sustiva

Answer 29

zovirax

Question 30

This is an inhibitor of influenza virus neuraminidase which prevents viral progeny from detaching from cell envelope a.selzentry b.oseltamivir c.valtrex d.zovirax

Answer 30

oseltamivir

Question 31

A major contrainidcation of this drug is that it interferes with influenza vaccine effectiveness | a.tamiflu b.zovirax c.baraclude d.sovaldi

Answer 31

tamiflu

Question 32

When on this antiviral there is a possible DI with foscarnet,varicella and zoster vaccine, therfore caution must be taken.Which of the following drugs is this? a.elbasivir/grazoprevir b.emtricitabine/tenofovir c.acyclovir d.reyataz

Answer 32

acyclovir

Question 33

BBW for these two drugs is HBV reactivation a.elbasivir/grazoprevir b.truvada c.sustiva d.baraclude e.sovaldi

Answer 33

* elbasivir/grazoprevir * sovaldi

Question 34

Use in pregancy and with amiodarone as well as p-glycoprotein inhibitors/inducers are major contraindicatios for this drug a.valtrex b.sofosbuvir c.mavyret d.tamiflu

Answer 34

sofosbuvir

Question 35

This drug has a BBW of HBV resistance in HIV coinfected, disease exacerbation upon d/c, lactic acidosis a.insentress b.sustiva c.entecavir d.zepatier

Answer 35

entecavir

Question 36

Ribavirin and ganciclovir are contraindicated in patients on this treatment a.efavirenz b.glecaprevir/pinremtasvir c.acyclovir d.baraclude

Answer 36

baraclude

Question 37

BBW for this antiviral include HBV exacerbation,lactic acidosis, drug resistance with PrEP a.voltrex b.truvada c.zovirax d.insentress

Answer 37

truvada

Question 38

CI: Hypersensitivity, bepridil, cisapride, elbasvir, grazoprevir, midazolam, pimozide, triazolam, St. John’s wort, or ergot alkaloids * DI: various CYP enzymes, oral contraceptives, QTc prolonging agents Which of the following drugs does this reference a.entecavir b.Efavirenz c.maraviroc d.raltegravir

Answer 38

efavirenz

Question 39

Antacid (separate dosing), Cyp 3a4, PR or QTc prolongers, oral contraceptives, PPI and H2 blockers, UGT1A1 sybstrates are contratindications listed for which drugs? a.Reyatza b.acyclovir c.entacavir d.oseltamivir

Answer 39

reyatza

Question 40

DI: antacids (separate dosing), fosamprenavir, rifampin, PPI and H2 blockers a. Zovirax b.selzentry c.atazanavir d.insentress

Answer 40

insentress

Question 41

CI: CrCl less than 30 mL/min or ESRD who are taking potent CYP3A4/5 inhibitors or inducers * DI: Cyp3A4 inhibitors or inducers a.maraviroc b.valtrex c.sustiva d.zepatier

Answer 41

maraviroc