Antiviral 🥦,,pharma 5 Flashcards

1
Q

M2 ion channel inhibitors

A

Amantadanes: M2 ion channel

🌸Amantadine and Rimantadine 🌸
Anti-parkinsonism activity
Available since 1960’s Tricyclic primary amines block M channel to inhibit viral uncoating Active against influenza A including non-human subtypes

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2
Q

Neuraminidase inhibitor

A

by preventing its reproduction by budding from the host cell.
Zanamivir and Oseltamivir

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3
Q

acyclovir

A

Interferes with DNA polymerase to inhibit DNA replication via chain termination

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