Anti HF

Question 1

TX incre. Survival

Answer 1

👾. RAAS antagonism
• ACE I / ARB

• Aldosterone blockade
👾b blocker

Question 2

Hypertensive Emergencies

• Very high BP (often over 220/120 mmHg)
• Associated with acute complications – pulmonary oedema, renal failure, aortic dissection etc
• Need to reduce BP by ~20% or to 100 mmHg diastolic within 1-2 hours

Answer 2

Sodium Nitroprusside: Mimics the action of endogenous

nitric oxide on vascular smooth muscle, acting as a potent vasodilator

• Intravenous use with powerful rapid onset and offset
• Breakdown to cyanide – caution in liver disease, but renal excretion. Avoid prolonged use (>72 hours).