Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Microbiology > Antiviral Drugs > Flashcards

Antiviral Drugs Flashcards

You may prefer our related Brainscape-certified flashcards:
Biology 101 flashcards
1
Q

Inhibitors of early events (5)

A

Amatadine, Rimantadine
Enfuvirtide
Maraviroc
Palivizumab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Afftected virus - amantadine

A

Influenza A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Prevents Uncoating (2)

A

Amantadine & Rimantadine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Side effects - amantadine

A

CNS alterations; dizziness, ataxia, insomnia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Alternate drug - amantadine

A

Rimantadine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Affected virus - Enfurvirtide

A

HIV virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Mechanism - amantadine

A

Blocks ion channel of M2 matrix proteins; prevents uncoating; no transcription

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Affected virus - Maraviroc

A

HIV virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Mechanism - Enfurvirtide

A

Binds gp41; fusion inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Affected virus - Palivizumab

A

Respiratory syncytial virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Mechanism - Palivizumab

A

Monoclonal antibody; binds to fusion protein of virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Uses - Palivizumab

A

Prevents bronchiolitis & pneumonia in premature and immunocompromised patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Inhibitors of Herpes virus - nucleoside inhibitors (6)

A 
Acyclovir - famciclovir, valacyclovir & penciclovir
Ganciclovir - valganciclovir
Cidofovir
Vidarabine
Idoxuridine
Trifluoridine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Inhibitors of Herpes virus - non-nucleoside inhibitors (1)

A

Foscarnet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Mechanism - Acyclovir

A

Guanosine analog
Monophosphorylated by HSV/VZV encoded THYMIDINE KINASE
Triphosphate formed by Cellular kinases
Inhibits viral DNA polymerase by chain termination

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Clinical use - Acyclovir

A

HSV 1&2 and VZV; no CMV
No affect on latent forms

Hsv —> genital lesions & encephalitis

18
Q

Side effects - Acyclovir

A

CNS toxicity & renal toxicity (obstructive crystalline nephropathy & acute renal failure)

19
Q

Valacyclovir & famciclovir

A

Valacyclovir - herpes genitalis & zoster

Famciclovir - herpes zoster

20
Q

Mechanism- Maraviroc

A

Binds CCR-5; fusion inhibitor; prevents interaction of gp120 with CCR-5; docking inhibitor

Microbiology (46 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions