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Boards First Aid and Kaplan > Antiprotozoal Agents > Flashcards

Antiprotozoal Agents Flashcards

1
Q

What is the DOC for amebiasis?

A

Metronidazole (diloxanide for noninvasive intestinal amebiasis)

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2
Q

What is the DOC for toxoplasmosis?

A

Pyrimethamine + sulfadiazidine

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3
Q

What is the DOC for leishmaniasis?

A

Stibogluconate

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4
Q

What is the DOC for giardiasis?

A

Metronidazole (backpacker’s diarrhea from contaminated water/food)

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5
Q

What is the DOC for trypanosomiasis?

A
  • Nifurtimox (Chagas disease)

- Arsenicals (African)

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6
Q

What is the DOC for trichomoniasis?

A

Metronidazole (treats both partners)

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7
Q

Chloroquine alone is the treatment for what types of malaria?

A

Falciparum and malariae

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8
Q

Chloroquine + primaquine is the treatment for what types of malaria?

A

Vivax and ovale

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9
Q

What is used for prophylaxis is chloroquine-resistant regions?

A

Mefloquine

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10
Q

What is used for treatment chloroquine-resistant regions?

A

Quinine +/- either doxycycline or clindamycin or pyrimethamine

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11
Q

What are the possible side effects of primaquine and quinine?

A

-Hemolytic anemia in G6PD deficiency

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12
Q

What antimalarial drug causes cinchonism?

A

Quinine

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13
Q

What drugs are used for most intestinal nematodes (worms)?

A
  • Albendazole

- Pyrantel pamoate

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14
Q

What is the MOA of albendazole?

A

Decreased glucose uptake and microtubular structure

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15
Q

What is the MOA of pyrantel pamoate?

A

Nm agonist (can cause spastic paralysis)

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16
Q

What drug is used for most cestodes (tapeworms) and trematodes (flukes)?

A

Praziquantel

17
Q

What is the MOA of praziquantel?

A

Increased Ca influx and vacuolization

Boards First Aid and Kaplan (19 decks)

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