Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Antineoplastic and Immunosupressant Drugs > Flashcards

Antineoplastic and Immunosupressant Drugs Flashcards

1
Q

When cancer returns “____ _____” are used to get it under control again

A

Rescue drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Antineoplastic drugs that act at all stages of the cycle except resting

A

Cell-Cycle Non-specific drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Antineoplastic drugs that act only at certain phases and are most effective against fast growing neoplasms

A

Cell-cycle specific drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Lymphoproliferative, Myeloproliferative disorders, mast cell tumors, carcinomas, and sarcomas are all indications for ______ drugs

A

Antineoplastic drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

These drugs must be used with care as they are teratogenic/mutagenic/carcinogenic

A

Antineoplastic drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Antineoplastic drugs have the potential to cause cancer when exposed to ____ or _____ _____

A

skin or mucous membranes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What must be worn when handling antineoplastic drugs to avoid exposure?

A

Particulate respiratory mask

Non-permeable gloves or 2 pairs of surgical gloves

General PPE (lab coats, gowns, etc)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Leak proof, puncture resistant containers must be used to dispose antineoplastic contaminated materials and must be labeled as “______ _____” and disposed of by specific companies

A

Cytotoxic waste

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Dosage calculation of antineoplastic drugs is usually based on _______________ (square meters)

A

Body surface area

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Agents that corss link DNA to inhibit its replication

A

Alklyating agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Cyclophosphamide (Cytoxan), Chlorambucil (Leukeran) and Melphalan (Alkeran) are all _____ _____

A

Alkylating agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Side effects of these drugs include myelosuppression and hemorrhagic cystitis

A

Alkylating agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Cell cycle specific drugs that affect DNA synthesis

A

Antimetabolites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Methotrexate, 5-Florouracil and Cytosine Arabinoside (Cytosar) are all examples of ________

A

Antimetabolites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What antimetabolite is contraindicated in cats?

A

5-Florouracil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Derived from plants to stop cancer cell division

A

Plant alkaloids

17
Q

Natural alkaloids derived from the ______ ____

A

Periwinkle plant

18
Q

Vincristine (Oncovin) and Vinblastine (Alkaban AQ) are both examples of _____ ____

A

Plant alkaloids

19
Q

Inhibit RNA, DNA, and protein synthesis, derived from streptomyces soil fungi

A

Antibiotic agents

20
Q

Administered prior to the drug to inhibit anaphylaxis

A

H1 Antihistamines

21
Q

______ is a strong vesicant. Tissue sloughing follows extravastion

A

Doxorubicin

22
Q

Drugs used for tumor suppression, anti-inflammatory effects, and reproductive cancers, mast cell tumors

A

Steroid drugs

23
Q

______ will cause necrosis, therefore great care must be taken to ensure the IV cath is in the vein

A

Extravasation

Pharmacology (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions