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Microbiology > Antimicrobials > Flashcards

Antimicrobials Flashcards

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Biology 101 flashcards
0
Q

Beta lactam antibiotics

A

Penicillin

Cephalosporins

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1
Q

The most selective antibiotics with high therapeutic index

A

Cell wall inhibitors

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2
Q

This cell wall inhibitor inhibits synthesis of peptidoglycan precursors and transport of precursors

A

Bacitracin

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3
Q

Penicillinase resistant penicillin drugs

A

Methicillin
Nafcillin
Oxacillin

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4
Q

Most potent inhibitor

A

Glacolamic

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5
Q

Blocks the initial step in protein synthesis

A

Linezolid

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6
Q

Drugs which bind to the 50s ribosomal unit

A

Chlorampenicol
Erythromycin
Lincomycin
Lindamycin

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7
Q

Drugs which bind to 30s ribosomal unit

A

Tetracyclines
Spectinomycin
Minoglycosides

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8
Q

Nucleic acid inhibitor which inhibits RNA polymerase

A

Rifampicin

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9
Q

Anti-TB drug

A

Rifampicin

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10
Q

Inhibits nucleic acid

A

Quinolones

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11
Q

Disrupts DNA

A

Metronidazole

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12
Q

This cell membrane inhibitor is applied to skin/ topical antibiotic

A

Polymyxin B

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13
Q

Inhibits folic acid metabolism

A

SMZ( sulfamethoxazole)

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14
Q

Blocks tetrahydrofolate synthesis

A

Trimethoprim (TMP)

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15
Q

Interferes with synthesis of folic acid

A

Dapsone

16
Q

Inhibits the synthesis of cord factor

A

Isoniazid

17
Q

Natural consequence of drug exposure

A

Antibiotic resistance

18
Q

Enzymes that chemically inactivate beta lactam

A

Beta lactamases

19
Q

Enzymes found on plasmids

A

Class A enzymes

20
Q

Beta lactamases that can inactivate extended-spectrum cephalosporins, penicillin and aztreonam

A

ESBLs (extended spectrum beta lactamases)

21
Q

Active against ESBL producing strains

A

Carbapenems

22
Q

Beta lactamase inhibitor which inhibits esbl activity

A

Clavulinic acid

Microbiology (10 decks)

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