Antihypertensives

Question 1

Peripherally acting alpha 1 blockers

Answer 1

“Zosin”
Dilated arteries and veins
Increase urine flow

“Flowmax” not used to control BP but symptomatic control of BPH

Question 2

Beta blockers

Answer 2

“Olol”
Reduction of HR
Reduced secretion of renin but

Question 3

Dual Alpha 1 and beta blocker

Answer 3

Carvedilol (Coreg)
Reduction HR and vasodilation

Contra - severe bradycardia asthma

Question 4

Adrenergic drugs

Answer 4

All hypertension
Glaucoma

AE - orthostatic hypertension, sexual dysfunction

Question 5

Angiotensin - converting enzyme inhibitors (ACE)

Answer 5

“Pril”
HF & renal protective effects for diabetes

AE - dry nonproductive cough, possible hyperkalemia, angioedema

Can cause renal impairment - identify with serum creatinine
Also check potassium levels

Question 6

_____ & _____ are not pro drugs

Answer 6

Catopril and lisinopril are inactive in their administered form and must be metabolized in the liver
Used for patient with liver dysfunction

Question 7

Captopril

Answer 7

Shortest half life

Question 8

Enalapril

Answer 8

Only ACE in both oral and parenteral form

Question 9

Angiotensin II receptor blockers (ARBs)

Answer 9

“Sartan”
Does not cause dry cough
Block vasoconstriction and secretion of aldosterone

AE - fatigue (takes a couple of weeks to adjust), and chest pain

Question 10

Calcium Channel blockers (CCBs)

Answer 10

Can also be used for migraine headaches and Raynauds syndrome

Smooth muscle relaxation

Question 11

Diuretics

Answer 11

Easiest to do
Thiazide diuretics most common
You dont lose potassium

Question 12

Vasodilators

Answer 12

“Nitro”

Sodium nitroprusside and IV diazoxide are reserved for hypertensive emergencies

Question 13

Treatment of pulmonary hypertension

Answer 13

Bosentan (Tracleer)