Antihistamine Flashcards

1
Q

What is the most common hypersensitivity reaction?

A

Type 1 - Allergies and Analphylaxis

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2
Q

What 2 types of cells are involved in Type 1?

A

Mast cells and Basophils

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3
Q

Type 1 causes a release of ___________ mediators

A

vasoactive

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4
Q

What is the most important vasoactive mediator?

A

Histamine

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5
Q

What can histamine result in?

A

Bronchoconstriction
Pruritis
GI signs
Dilation of small blood vessels

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6
Q

On top of release of histamine, what do antihistamines block?

A

Histamine receptors (ie. Bronchial smooth muscles)

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7
Q

Antihistamines work best in a ______________ situation

A

Preventative

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8
Q

What are common antihistamines?

A

Hydroxyzine
Chlorpheniramine
Diphenhydramine

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9
Q

What are the 4 main uses for antihistamines?

A

Allergies
Antiemetic Effects
Appetite Stimulant
Respiratory Disease

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10
Q

What are the two common respiratory diseases antihistamines are used for?

A

COPD in horses
Feline Asthma

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