Antihistamine Flashcards
What is the most common hypersensitivity reaction?
Type 1 - Allergies and Analphylaxis
What 2 types of cells are involved in Type 1?
Mast cells and Basophils
Type 1 causes a release of ___________ mediators
vasoactive
What is the most important vasoactive mediator?
Histamine
What can histamine result in?
Bronchoconstriction
Pruritis
GI signs
Dilation of small blood vessels
On top of release of histamine, what do antihistamines block?
Histamine receptors (ie. Bronchial smooth muscles)
Antihistamines work best in a ______________ situation
Preventative
What are common antihistamines?
Hydroxyzine
Chlorpheniramine
Diphenhydramine
What are the 4 main uses for antihistamines?
Allergies
Antiemetic Effects
Appetite Stimulant
Respiratory Disease
What are the two common respiratory diseases antihistamines are used for?
COPD in horses
Feline Asthma