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Internmedicin > Antibiotika > Flashcards

Antibiotika Flashcards

1
Q

erysipelas

A

betahemolyserande streptokocker

bensyl pc

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2
Q

pneumoni

A

pneumokock + meningokock= bensyl pc

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3
Q

kåvepenin

A

tonsillit, otit, sinuit, pneumoni, erysipelas

strptok, pneumok, meningok.

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4
Q

sårinfektion

A

staf aureus

heracillin

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5
Q

selexid

A

Pivmecillinam

nedre UVI

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6
Q

Tazocin

A

buk gall inf
övre UVI
IVA pneumoni

gram neg

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7
Q

Claforan

A

övre UVI
meningit
OKLAR SEPSIS

HI, beta-lakt-pos, gram-neg

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8
Q

atypisk pneumoni

A

mycoplasma, klamydia

doxyferm (doxycyklin)

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9
Q

Ery- Max

A

erytromycin

atypisk pneumoni

mycoplasma, legionella

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10
Q

vancomycin

A

vancocin

resistenta grampos

MRSA, KNS

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11
Q

Flagyl

A

bukinf, clost dificile enterit

anaerober, clost dificile

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12
Q

fyra grupper av antibiotikaangreppspunkter

A

cellväggssyntes-hämmare

proteinsyntes-hämmare

DNA realisations och transkriptions-hämmare

folsyrasytes-hämmare

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13
Q

cellväggssyntes-hämmare

A

beta laktamatibiotika

penicilliner
cefalosporiner
karbapenemer

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14
Q

proteinsyntes-hämmare

A

erythromycin
klindamycin
tetracykliner
aminoglykosider

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15
Q

DNA realisations och transkriptions-hämmare

A

kinoloner

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16
Q

folsyrasytes-hämmare

A

trimetoprim

sulfamethoxazol

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17
Q

penicilliner

A 
PcV
Bensyl-Pc
Amoxicillin
Ampicillin
Flokloxacillin
Kloxacillin
Mecillinam
Piperacillin-tazobaktam
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18
Q

cefalosporiner

A

cefotaxim
ceftazidim

ceftriaxon
cefuroxim

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19
Q

karbapenemer

A

imipenemer

meropenem

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20
Q

aminoglykosider

A

gentamycin

amikacin

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21
Q

kinoloner

A

ciprofloxacin
levofloxacin
moxifloxacin

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22
Q

folsyraantagonister

A

trimetoprimsulfa

23
Q

tetracykliner

A

doxycyklin

24
Q

makrolider

A

erythromycin

25
Q

linkosamider

A

klindamycin

26
Q

glykopeptider

A

vankomycin

27
Q

imidazolderivat

A

metronidazol

28
Q

tonsilit,otit, pnemoni, erysipelas

A

PcV- kåvepenin

Bensyl-Pc

29
Q

pneumoni (empirisk för KOL pat, täcker HI)

A

amoxicillin - amimox

30
Q

hudinfektion abscesser (postop)

A

flokloxacillin- heracillin

kloxacillin - ekvacillin

31
Q

sepsis, bukinf, leverinf

A

piperacillin-tazobaktam (tazocin)

32
Q

Vilka bakterier riktar man nej mot vid hud inf och vilken beh?

A

S. Aurerus - flukloxacillin/ kloxacillin

Betahemolyserande grupp A strep (GAS) - PcV/PcG

Osäker? Flukloxacillin/ kloxacillin

33
Q

bactericid

A

dödar bakterien

betalaktamasantibiotika, aminoglykosider, kinoloner

34
Q

bakteriostatisk

A

hämmar bakterietillväxten (kan börja växa efter avslutad beh)

ex klindamycin

35
Q

restriktivitet med antibiotika

A 
biverkningar (individ och miljö)
kostnader
ekologiska aspekter 
   rubbning av normalflora
   svamp
   selektion av resistenta stammar
36
Q

SIR-systemet

A

S- känslig
I- intermediär
R- resistent

37
Q

resistens typer

A

naturlig/förvärvad

in vitro - bakterien resistent vid labtester

in vivo - bakterien känslig men ab kommer ej åt (abscess, biofilm)

38
Q

resistensmekanismer

A

PBP - PNSP, MRSA

effluxpump (som pumpar ut ab)

porin

enzym - ESBL

39
Q

renal utsöndring

A

aminoglykosider
betalaktam ab
glykopeptider
levofloxacin

40
Q

blandad elimination

A

ciprofloxacin
doxycyklin
sulfonamider
trimetoprim

41
Q

metabolism i lever

A

fusidinsyra
makrolider/linkosamider
nitromidazoler

42
Q

beh borrelia

A

doxyferm 100 mg x 2

lymfocytom: 14 d
akrodermatit: 3 v
artrit: 14 d

neuroborrelios: 200 mg 14 d

43
Q

ABM byte till po beh

A

meningokocker. Bensyl Pc 7d (omgivningsprofylax)
pneumokocker: Bensyl Pc 10-14 d

HI: Ampicillin 10-14 d

Listeria monocytogenes: Ampicillin 3 v

44
Q

hjärnabcess beh

A

ev neurokirurgdränage

cefotaxim + metronidazol

45
Q

enterovirus meningit beh

A

50-60 % av serösa meningiten

symtomatisk beh, lugn och ro, vätska, smärtlindring.

46
Q

hermes meningit beh

A

HSV-2

valacyklovir po

profylax om täta recidiv

47
Q

herpesencephalit beh

A

HSV-1

acyklovir iv 3 v
ev steroider
ev krampprofylax

48
Q

TBE beh

A

symtomatisk, lugn och ro, vätska, smärtlindring, antiemetica

vaccinprofylax, 3 doser.

49
Q

hepatit A profylax

A

profylax: gammaglobulin/vaccin,
postexpositionsprofylax: -II- inom 2 v

50
Q

hepatit E beh

A

ribavirin vid kronisk samt fulminant

ingen profylax

51
Q

hepatit B beh

A

pegylerat IFN (12 mån), entecavir eller tenofovir.

profylax: vaccin
postexpositionsprofylax: vaccin/immunoglobulin.

52
Q

Hepatit D beh

A

pegylerat IFN

profylax: Hep B vaccination

53
Q

hepatit C beh

A

proteashämmare
NS5A hämmare.

harvoni, Viekirax

Internmedicin (10 decks)

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