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Antibiotika Flashcards

1
Q

erysipelas

A

betahemolyserande streptokocker

bensyl pc

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2
Q

pneumoni

A

pneumokock + meningokock= bensyl pc

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3
Q

kåvepenin

A

tonsillit, otit, sinuit, pneumoni, erysipelas

strptok, pneumok, meningok.

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4
Q

sårinfektion

A

staf aureus

heracillin

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5
Q

selexid

A

Pivmecillinam

nedre UVI

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6
Q

Tazocin

A

buk gall inf
övre UVI
IVA pneumoni

gram neg

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7
Q

Claforan

A

övre UVI
meningit
OKLAR SEPSIS

HI, beta-lakt-pos, gram-neg

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8
Q

atypisk pneumoni

A

mycoplasma, klamydia

doxyferm (doxycyklin)

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9
Q

Ery- Max

A

erytromycin

atypisk pneumoni

mycoplasma, legionella

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10
Q

vancomycin

A

vancocin

resistenta grampos

MRSA, KNS

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11
Q

Flagyl

A

bukinf, clost dificile enterit

anaerober, clost dificile

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12
Q

fyra grupper av antibiotikaangreppspunkter

A

cellväggssyntes-hämmare

proteinsyntes-hämmare

DNA realisations och transkriptions-hämmare

folsyrasytes-hämmare

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13
Q

cellväggssyntes-hämmare

A

beta laktamatibiotika

penicilliner
cefalosporiner
karbapenemer

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14
Q

proteinsyntes-hämmare

A

erythromycin
klindamycin
tetracykliner
aminoglykosider

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15
Q

DNA realisations och transkriptions-hämmare

A

kinoloner

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16
Q

folsyrasytes-hämmare

A

trimetoprim

sulfamethoxazol

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17
Q

penicilliner

A 
PcV
Bensyl-Pc
Amoxicillin
Ampicillin
Flokloxacillin
Kloxacillin
Mecillinam
Piperacillin-tazobaktam
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18
Q

cefalosporiner

A

cefotaxim
ceftazidim

ceftriaxon
cefuroxim

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19
Q

karbapenemer

A

imipenemer

meropenem

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20
Q

aminoglykosider

A

gentamycin

amikacin

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21
Q

kinoloner

A

ciprofloxacin
levofloxacin
moxifloxacin

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22
Q

folsyraantagonister

A

trimetoprimsulfa

23
Q

tetracykliner

A

doxycyklin

24
Q

makrolider

A

erythromycin

25
linkosamider
klindamycin
26
glykopeptider
vankomycin
27
imidazolderivat
metronidazol
28
tonsilit,otit, pnemoni, erysipelas
PcV- kåvepenin | Bensyl-Pc
29
pneumoni (empirisk för KOL pat, täcker HI)
amoxicillin - amimox
30
hudinfektion abscesser (postop)
flokloxacillin- heracillin | kloxacillin - ekvacillin
31
sepsis, bukinf, leverinf
piperacillin-tazobaktam (tazocin)
32
Vilka bakterier riktar man nej mot vid hud inf och vilken beh?
S. Aurerus - flukloxacillin/ kloxacillin Betahemolyserande grupp A strep (GAS) - PcV/PcG Osäker? Flukloxacillin/ kloxacillin
33
bactericid
dödar bakterien betalaktamasantibiotika, aminoglykosider, kinoloner
34
bakteriostatisk
hämmar bakterietillväxten (kan börja växa efter avslutad beh) ex klindamycin
35
restriktivitet med antibiotika
``` biverkningar (individ och miljö) kostnader ekologiska aspekter rubbning av normalflora svamp selektion av resistenta stammar ```
36
SIR-systemet
S- känslig I- intermediär R- resistent
37
resistens typer
naturlig/förvärvad in vitro - bakterien resistent vid labtester in vivo - bakterien känslig men ab kommer ej åt (abscess, biofilm)
38
resistensmekanismer
PBP - PNSP, MRSA effluxpump (som pumpar ut ab) porin enzym - ESBL
39
renal utsöndring
aminoglykosider betalaktam ab glykopeptider levofloxacin
40
blandad elimination
ciprofloxacin doxycyklin sulfonamider trimetoprim
41
metabolism i lever
fusidinsyra makrolider/linkosamider nitromidazoler
42
beh borrelia
doxyferm 100 mg x 2 lymfocytom: 14 d akrodermatit: 3 v artrit: 14 d neuroborrelios: 200 mg 14 d
43
ABM byte till po beh
meningokocker. Bensyl Pc 7d (omgivningsprofylax) pneumokocker: Bensyl Pc 10-14 d HI: Ampicillin 10-14 d Listeria monocytogenes: Ampicillin 3 v
44
hjärnabcess beh
ev neurokirurgdränage cefotaxim + metronidazol
45
enterovirus meningit beh
50-60 % av serösa meningiten symtomatisk beh, lugn och ro, vätska, smärtlindring.
46
hermes meningit beh
HSV-2 valacyklovir po profylax om täta recidiv
47
herpesencephalit beh
HSV-1 acyklovir iv 3 v ev steroider ev krampprofylax
48
TBE beh
symtomatisk, lugn och ro, vätska, smärtlindring, antiemetica | vaccinprofylax, 3 doser.
49
hepatit A profylax
profylax: gammaglobulin/vaccin, postexpositionsprofylax: -II- inom 2 v
50
hepatit E beh
ribavirin vid kronisk samt fulminant ingen profylax
51
hepatit B beh
pegylerat IFN (12 mån), entecavir eller tenofovir. profylax: vaccin postexpositionsprofylax: vaccin/immunoglobulin.
52
Hepatit D beh
pegylerat IFN profylax: Hep B vaccination
53
hepatit C beh
proteashämmare NS5A hämmare. harvoni, Viekirax

Internmedicin (10 decks)

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