Antibiotics Flashcards

1
Q

Antibiotics are used to treat

A

Acute infections
Chronic infections
Infections such as periodontitis
For prophylaxis such as patients -
Skull fractures
Immunocompromised hosts
Radiotherapy recipients
Patients with protheses (hip)

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2
Q

Antibiotic + Microbe

A

Eukaryotes-
Fumagillin- Aspergillus fumigatus
Penicillin- Penicillium notatum
Prokaryote-
Nystatin- Streptomyces noursei

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3
Q

How do antibiotics work?

A

Inhibition of cell wall synthesis- penicillin.
Inhibition of protein synthesis-tetracycline.
Inhibition of nucleic acid synthesis- quinolones.
Disruption of cell membrane function- polymyxin.

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4
Q

Antifungal medication

A

Polyenes- Causes plasma membrane to leak ions.

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5
Q

Oral candidosis medication

A

Fluconazole capsule
Issues are that it could cause fluconazole resistance.

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6
Q

Antibiotics name and mechanism of action

A

Penicillin and Bacitracin- Inhibits cell wall synthesis
Macrolides- Inhibits protein synthesis
Rifamycin- Inhibits RNA synthesis

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7
Q

Antibiotic side effects:
Beta-lactams
Tetracycline
Rifampin

A

Beta-lactams- Allergy (hives)
Tetracycline- Brown/ yellow teeth staining.
Rifampin- Red man syndrome

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8
Q

What are antibiotics

A

Antibiotics are a chemical substance that kill or inhibits the growth of bacteria.

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