antibiotica Flashcards

1
Q

Welke aangrijpingspunten heeft antibiotica?

A
  • bacteriele celwand en celmembraan
  • antibiotica die de bacteriele nucleinezuur synthese remmen
  • antibiotica die eiwitsynthese in het ribosoom remmen
  • synthese foliumzuur –. blokkeren aanmaak foliumzuur (essentieel basis RNA/DNA en eiwitten
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2
Q

welke small spectrum penicilline zijn er?

A
  • penicilline: benzyl penicilline iv en feneticilline
  • fluclozacilline
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3
Q

welk breedspectrum peniciline is er?

A

amoxicilline

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4
Q

wat is een bacteriostatisch AB?

A

remt eiwitsynthese –> geen vermenigvuldiging

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5
Q

hoe werkt flucloxacilline?

A

verstoort celwandsynthese, bactericide AB

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6
Q

wat zijn indicaties voor flucloxacilline?

A
  • huidbacterien
  • profylactische hartinfecties
  • gewrichtsinfecties
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7
Q

wanneer amoxicilline?

A

gram positieve als streptokokken en sommige negatieve staven

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8
Q

wanneer amoxicilline/clavulaanzuur?

A
  • bacteriele keel neus oor ontstekingen,
  • community aqcuired pneumonie
  • uwi
  • infectie door bijtwond
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9
Q

Hoe werken tetracyclinen als doxycycline?

A

remt eiwitsynthese in ribosoom

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10
Q

wanneer doxycycline?

A

grampos, neg en profylaxe

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11
Q

welke middelen bij UWI?

A
  • nitrofurantoine
  • fosfomycine
  • trimethoprim
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12
Q
A
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