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step 1 pharm > anti-protozoans/helminths > Flashcards

anti-protozoans/helminths Flashcards

1
Q

toxoplasmosis treatment

A

pyrimethamine

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2
Q

trypanosoma brucei treatment

A

sumarin and melarsoprol

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3
Q

trypanosoma cruzi treatment

A

nifurtimox

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4
Q

leishmaniasis treatment

A

sodium stibogluconate

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5
Q

chloroquine moa

A

blocks detoxification of heme into hemozoin; heme accumulates and is toxic to plasmodia

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6
Q

chloroquine clinical use

A

treatment of plasmodial species other than P. falciparum

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7
Q

chloroquine resistance

A

membrane pump that decreases intracellular concentration of the drug

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8
Q

plasmodium falciparum treatment

A

atovaquone/proguanil or artemether/lumefantrine; if life threatening, use quinidine

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9
Q

chloroquine toxicity

A

retinopathy; pruritus

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10
Q

schistosoma treatment

A

praziquantel

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11
Q

antihelminth drugs

A

mebendazole, pyrantel pamoate, ivermectin, diethylcarbamazine praziquantel

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12
Q

antihelminth moa

A

immobilize helminths

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step 1 pharm (20 decks)

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