ANS Flashcards

1
Q

Where ate the cell bodies of the preganglionic sympathetic neurons located? What

A

In the intermediolateral (IML) cell column of the spinal cord gray matter

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2
Q

Where do preganglionic axons in the sympathetic trunk synapse?

A

At the same level from which they originate or at a higher level

In some cases it can pass through on the way to another peripheral ganglion (prevertebral) outside of the sympathetic trunk.

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3
Q

Where do the sympathetics of the skin of the extremities and body wall originate?

A

In the IML of the spinal cord

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4
Q

What nerve root supplies the sympathetics to the skin and extremities and body walls.

A

T1-L2

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5
Q

What roots supplies the sympathetics to the organs of the thorax?

A

The central root of T1-T5

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6
Q

What nerve roots go to the sympathetics to the organs of the abdomen and pelvis?

A

Central root of T5-L1

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7
Q

What do the preganglionic nerves with cranial nerves III, VII, and IX synapse in?

A

They synapse in specific ganglia in the head

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8
Q

Where do preganglionic neurons with cranial nerve X synapse in?

A

They synapse in ganglia in the wall of the thoracic and abdominal organs.

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9
Q

Where did the preganglionic parasympathetic neurons for the sacral outflow travel to?

A

They exit the spinal cord via the ventral root of S2-S4 spinal nerves and travel to their target organs via the pelvic splanchnic nerve is where the synapse in the ganglia in the wall of the lower abdominal and pelvic organs.

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10
Q

What is the epimysium?

A

Sense connective tissue that surrounds the entire muscle and is synonymous with deep fascia.

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11
Q

What is the perimysium?

A

Connective tissue that surrounds a group of fibers to form a fascicles.
It conveys the large blood vessels and nerves into the muscle.

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12
Q

What is the endomysium?

A

Delicate connective tissue which surrounds individual muscle fibers

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13
Q

What does type one muscle fiber contain a lot of?

A

Myoglobin and mitochondria

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14
Q

How is ATP generated in type two muscle fibers?

A

By anaerobic glycolysis

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15
Q

What is the plasma membrane of muscle cells referred to as?

A

Sarcolemma

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16
Q

Where are the components of myofibrils?

A

Z lines, I band, A band, H band, and M line

17
Q

What are characteristics of Z lines?

A

The define the boundary of each sacromere

They contain actin binding protein, alpha actinin

18
Q

What are characteristic of the I band?

A

Composed exclusively of actin thin filaments.

Width decreases during contraction

19
Q

What are characteristics of the A band?

A

Composed of overlapping thick and thin filaments

Width remains constant during contraction

20
Q

What are characteristics of the H band?

A

Central region of the A band contains only thick filaments

Width decreases during contraction

21
Q

What are characteristics of the M-line?

A

Middle of the H band.

Overlapping tails of thick filaments

22
Q

Which complexes does F actin form with?

A

Tropomyosin and troponin complexes (I,T,C)

23
Q

What does tropomyosin consist of?

A

Two polypeptides twisted around each other running in groove formed by F actin filaments

24
Q

What does tropomyosin bind?

A

Troponin T of troponin complex

25
Q

What does troponin I do?

A

Inhibits binding of myosin to Actin and troponin C that binds calcium

26
Q

What does nebulin do?

A

Extends from Z line along length of thin filament: it acts as a stabilizer for thin filaments

27
Q

What do the myosin tails do?

A

They allow several mice and molecules to form a filament

28
Q

What is Titin?

A

Very large protein that extends from Z line to center of sarcomere. It controls assembly of thick filaments and provides elasticity to sarcomere

29
Q

Where does depolarization spread to?

A

From sacrolemma to T tubules which transport signal to inferior or muscle cell

30
Q

What senses depolarization of T tubule?

A

L type calcium channel in the membrane of the T tubule

31
Q

What happens after L type Calcium channels sense depolarization?

A

It induces ryanodine-sensitive calcium channels in the membrane of the sarcoplasmic reticulum terminal cisternae

32
Q

What does the binding of troponin C cause?

A

It causes a conformational change in troponin. The change in troponin alters conformation of tropomyosin leaded to exposure of myosin binding sites

33
Q

How does the axon interact with muscle fiber?

A

Via the motor end plate or neuromuscular junction

34
Q

Contraction begins with release of what?

A

Acetylcholine

Acetylcholine binds to a receptor on muscle sacrolemma and causes depolarization of cell membrane

35
Q

What do proprioreceptors do?

A

They are sensory organs of skeletal muscle tendon and joints.

They provide feedback on contractile state of muscle, tension of tendon, and position of the joint

36
Q

What are the target organs of the sympathetics to organs of the thorax?

A

Heart, lungs, trachea, larynx, and blood vessels

37
Q

Where can the peripheral ganglia of sympathetics to organs of the abdomen and pelvis?

A

Celiac, superior mesenteric, inferior mesenteric, aorticorenal

38
Q

What are the targets of cranial nerve 7 and 9?

A

Salivary glands