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Pharmacology > ANS > Flashcards

ANS Flashcards

1
Q

main source of Norepinephrine

A

Long post-ganglion of sympha

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2
Q

main source of Epinephrine

A

Adrenal medulla

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3
Q

spinal roots of sympha

A

Thoracolumbar t1-12, L1-5

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4
Q

Spinal roots of Parasympha

A

Cranio-sacral
CN 10,9,7,3
S2,3,4

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5
Q

Steps in Synthesis in Acetylcholine

A

Transport and synthesis
Storage
Release
Termination

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6
Q

inhibits the Choline acetyltransferase in Transport and Synthesis

A

Hemicholinium

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7
Q

Inhibits the Step 2 storage in ACh synthesis

A

Vesamicol

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8
Q

inhibits the Step 3 release in Ach Synthesis

A

Botilinum toxin

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9
Q

Inhibits step 4 Termination in Ach Synthesis

A

indirect Cholinomimetics - Carbamate and organophophates

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10
Q

Cholinergic Agonist

A

mimics acetylcholine
DUMBBELLS
Diarrrhea/diaphoresis
Urination
Miosis
Bradycardia (M) Tachy (N)
Emesis
Lacrimation
Lethargy
Salivation

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11
Q

drug with moa as ONLY M3 selective

A

PIlocarpine
Cevimeline

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12
Q

reversal of Atropine poisoning

A

Physostigmine

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13
Q

DOPA is _______ to Dopamine, Dopamine ________ to NE

A

Decarboxylase; Hydoxylase

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14
Q

Inhibitor of the step 1 synthesis of Catecholamine

A

Metyrosine

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15
Q

The transfer of DOPA into vesicle is blocked by this drug

A

Reserpine

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16
Q

Diffusion and reuptake via NET and DAT in synaptic cleft is inhibited by

A

Cocaine and TCA

17
Q

DOC for alpha 1 agonist overdose

A

Phentolamine - adrenergic blocker

18
Q

DOC for acute asthma attack

A

beta 2 agonist - SABA LABA - Salbutamol

Pharmacology (10 decks)

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