ANS Flashcards
main source of Norepinephrine
Long post-ganglion of sympha
main source of Epinephrine
Adrenal medulla
spinal roots of sympha
Thoracolumbar t1-12, L1-5
Spinal roots of Parasympha
Cranio-sacral
CN 10,9,7,3
S2,3,4
Steps in Synthesis in Acetylcholine
Transport and synthesis
Storage
Release
Termination
inhibits the Choline acetyltransferase in Transport and Synthesis
Hemicholinium
Inhibits the Step 2 storage in ACh synthesis
Vesamicol
inhibits the Step 3 release in Ach Synthesis
Botilinum toxin
Inhibits step 4 Termination in Ach Synthesis
indirect Cholinomimetics - Carbamate and organophophates
Cholinergic Agonist
mimics acetylcholine
DUMBBELLS
Diarrrhea/diaphoresis
Urination
Miosis
Bradycardia (M) Tachy (N)
Emesis
Lacrimation
Lethargy
Salivation
drug with moa as ONLY M3 selective
PIlocarpine
Cevimeline
reversal of Atropine poisoning
Physostigmine
DOPA is _______ to Dopamine, Dopamine ________ to NE
Decarboxylase; Hydoxylase
Inhibitor of the step 1 synthesis of Catecholamine
Metyrosine
The transfer of DOPA into vesicle is blocked by this drug
Reserpine